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Dual mTORC1/2 inhibition compromises cell defenses against exogenous stress potentiating Obatoclax-induced cytotoxicity in atypical teratoid/rhabdoid tumors.
Parkhurst A, Wang SZ, Findlay TR, Malebranche KJ, Odabas A, Alt J, Maxwell MJ, Kaur H, Peer CJ, Figg WD, Warren KE, Slusher BS, Eberhart CG, Raabe EH, Rubens JA. Parkhurst A, et al. Among authors: kaur h. Cell Death Dis. 2022 Apr 28;13(4):410. doi: 10.1038/s41419-022-04868-9. Cell Death Dis. 2022. PMID: 35484114 Free PMC article.
Unbiased Metabolic Profiling Predicts Sensitivity of High MYC-Expressing Atypical Teratoid/Rhabdoid Tumors to Glutamine Inhibition with 6-Diazo-5-Oxo-L-Norleucine.
Wang SZ, Poore B, Alt J, Price A, Allen SJ, Hanaford AR, Kaur H, Orr BA, Slusher BS, Eberhart CG, Raabe EH, Rubens JA. Wang SZ, et al. Among authors: kaur h. Clin Cancer Res. 2019 Oct 1;25(19):5925-5936. doi: 10.1158/1078-0432.CCR-19-0189. Epub 2019 Jul 12. Clin Cancer Res. 2019. PMID: 31300448 Free PMC article.
MEK Inhibition Suppresses Growth of Atypical Teratoid/Rhabdoid Tumors.
Shahab S, Rubens J, Kaur H, Sweeney H, Eberhart CG, Raabe EH. Shahab S, et al. Among authors: kaur h. J Neuropathol Exp Neurol. 2020 Jul 1;79(7):746-753. doi: 10.1093/jnen/nlaa042. J Neuropathol Exp Neurol. 2020. PMID: 32472116 Free PMC article.
Disrupting LIN28 in atypical teratoid rhabdoid tumors reveals the importance of the mitogen activated protein kinase pathway as a therapeutic target.
Weingart MF, Roth JJ, Hutt-Cabezas M, Busse TM, Kaur H, Price A, Maynard R, Rubens J, Taylor I, Mao XG, Xu J, Kuwahara Y, Allen SJ, Erdreich-Epstein A, Weissman BE, Orr BA, Eberhart CG, Biegel JA, Raabe EH. Weingart MF, et al. Among authors: kaur h. Oncotarget. 2015 Feb 20;6(5):3165-77. doi: 10.18632/oncotarget.3078. Oncotarget. 2015. PMID: 25638158 Free PMC article.
The dual mTOR kinase inhibitor TAK228 inhibits tumorigenicity and enhances radiosensitization in diffuse intrinsic pontine glioma.
Miyahara H, Yadavilli S, Natsumeda M, Rubens JA, Rodgers L, Kambhampati M, Taylor IC, Kaur H, Asnaghi L, Eberhart CG, Warren KE, Nazarian J, Raabe EH. Miyahara H, et al. Among authors: kaur h. Cancer Lett. 2017 Aug 1;400:110-116. doi: 10.1016/j.canlet.2017.04.019. Epub 2017 Apr 25. Cancer Lett. 2017. PMID: 28450157 Free PMC article.
Targeting Notch signaling as a novel therapy for retinoblastoma.
Asnaghi L, Tripathy A, Yang Q, Kaur H, Hanaford A, Yu W, Eberhart CG. Asnaghi L, et al. Among authors: kaur h. Oncotarget. 2016 Oct 25;7(43):70028-70044. doi: 10.18632/oncotarget.12142. Oncotarget. 2016. PMID: 27661116 Free PMC article.
2,502 results