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Multiomic analysis identifies CPT1A as a potential therapeutic target in platinum-refractory, high-grade serous ovarian cancer.
Huang D, Chowdhury S, Wang H, Savage SR, Ivey RG, Kennedy JJ, Whiteaker JR, Lin C, Hou X, Oberg AL, Larson MC, Eskandari N, Delisi DA, Gentile S, Huntoon CJ, Voytovich UJ, Shire ZJ, Yu Q, Gygi SP, Hoofnagle AN, Herbert ZT, Lorentzen TD, Calinawan A, Karnitz LM, Weroha SJ, Kaufmann SH, Zhang B, Wang P, Birrer MJ, Paulovich AG. Huang D, et al. Among authors: kaufmann sh. Cell Rep Med. 2021 Dec 21;2(12):100471. doi: 10.1016/j.xcrm.2021.100471. eCollection 2021 Dec 21. Cell Rep Med. 2021. PMID: 35028612 Free PMC article.
Rad9 protects cells from topoisomerase poison-induced cell death.
Loegering D, Arlander SJ, Hackbarth J, Vroman BT, Roos-Mattjus P, Hopkins KM, Lieberman HB, Karnitz LM, Kaufmann SH. Loegering D, et al. Among authors: kaufmann sh. J Biol Chem. 2004 Apr 30;279(18):18641-7. doi: 10.1074/jbc.M313536200. Epub 2004 Feb 25. J Biol Chem. 2004. PMID: 14988409 Free article.
The role of checkpoint kinase 1 in sensitivity to topoisomerase I poisons.
Flatten K, Dai NT, Vroman BT, Loegering D, Erlichman C, Karnitz LM, Kaufmann SH. Flatten K, et al. Among authors: kaufmann sh. J Biol Chem. 2005 Apr 8;280(14):14349-55. doi: 10.1074/jbc.M411890200. Epub 2005 Feb 7. J Biol Chem. 2005. PMID: 15699047 Free article.
Heat shock protein 90 inhibition sensitizes acute myelogenous leukemia cells to cytarabine.
Mesa RA, Loegering D, Powell HL, Flatten K, Arlander SJ, Dai NT, Heldebrant MP, Vroman BT, Smith BD, Karp JE, Eyck CJ, Erlichman C, Kaufmann SH, Karnitz LM. Mesa RA, et al. Among authors: kaufmann sh. Blood. 2005 Jul 1;106(1):318-27. doi: 10.1182/blood-2004-09-3523. Epub 2005 Mar 22. Blood. 2005. PMID: 15784732 Free PMC article.
Overcoming S-phase checkpoint-mediated resistance: sequence-dependent synergy of gemcitabine and 7-ethyl-10-hydroxycamptothecin (SN-38) in human carcinoma cell lines.
Gálvez-Peralta M, Dai NT, Loegering DA, Flatten KS, Safgren SL, Wagner JM, Ames MM, Karnitz LM, Kaufmann SH. Gálvez-Peralta M, et al. Among authors: kaufmann sh. Mol Pharmacol. 2008 Sep;74(3):724-35. doi: 10.1124/mol.108.047787. Epub 2008 May 28. Mol Pharmacol. 2008. PMID: 18509065 Free PMC article.
Drug efflux by breast cancer resistance protein is a mechanism of resistance to the benzimidazole insulin-like growth factor receptor/insulin receptor inhibitor, BMS-536924.
Hou X, Huang F, Carboni JM, Flatten K, Asmann YW, Ten Eyck C, Nakanishi T, Tibodeau JD, Ross DD, Gottardis MM, Erlichman C, Kaufmann SH, Haluska P. Hou X, et al. Among authors: kaufmann sh. Mol Cancer Ther. 2011 Jan;10(1):117-25. doi: 10.1158/1535-7163.MCT-10-0438. Mol Cancer Ther. 2011. PMID: 21220496 Free PMC article.
1,195 results