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Page 1
Distinct Assemblies of Heterodimeric Cytokine Receptors Govern Stemness Programs in Leukemia.
Kan WL, Dhagat U, Kaufmann KB, Hercus TR, Nero TL, Zeng AGX, Toubia J, Barry EF, Broughton SE, Gomez GA, Benard BA, Dottore M, Cheung Tung Shing KS, Boutzen H, Samaraweera SE, Simpson KJ, Jin L, Goodall GJ, Begley CG, Thomas D, Ekert PG, Tvorogov D, D'Andrea RJ, Dick JE, Parker MW, Lopez AF. Kan WL, et al. Among authors: kaufmann kb. Cancer Discov. 2023 Aug 4;13(8):1922-1947. doi: 10.1158/2159-8290.CD-22-1396. Cancer Discov. 2023. PMID: 37191437 Free PMC article.
Sphingosine-1-phosphate receptor 3 potentiates inflammatory programs in normal and leukemia stem cells to promote differentiation.
Xie SZ, Kaufmann KB, Wang W, Chan-Seng-Yue M, Gan OI, Laurenti E, Garcia-Prat L, Takayanagi SI, Ng SWK, Xu C, Zeng AGX, Jin L, McLeod J, Wagenblast E, Mitchell A, Kennedy JA, Liu Q, Boutzen H, Kleinau M, Jargstorf J, Holmes G, Zhang Y, Voisin V, Bader GD, Wang JCY, Hannun YA, Luberto C, Schroeder T, Minden MD, Dick JE. Xie SZ, et al. Among authors: kaufmann kb. Blood Cancer Discov. 2021 Jan 1;2(1):32-53. doi: 10.1158/2643-3230.BCD-20-0155. Epub 2020 Dec 1. Blood Cancer Discov. 2021. PMID: 33458693 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 34238756
A primary hierarchically organized patient-derived model enables in depth interrogation of stemness driven by the coding and non-coding genome.
Boutzen H, Madani Tonekaboni SA, Chan-Seng-Yue M, Murison A, Takayama N, Mbong N, Wagenblast E, Orouji E, Arruda A, Mitchell A, Notta F, Minden MD, Lupien M, Kaufmann KB, Dick JE. Boutzen H, et al. Among authors: kaufmann kb. Leukemia. 2022 Nov;36(11):2690-2704. doi: 10.1038/s41375-022-01697-9. Epub 2022 Sep 21. Leukemia. 2022. PMID: 36131042 Free PMC article.
Sphingolipid Modulation Activates Proteostasis Programs to Govern Human Hematopoietic Stem Cell Self-Renewal.
Xie SZ, Garcia-Prat L, Voisin V, Ferrari R, Gan OI, Wagenblast E, Kaufmann KB, Zeng AGX, Takayanagi SI, Patel I, Lee EK, Jargstorf J, Holmes G, Romm G, Pan K, Shoong M, Vedi A, Luberto C, Minden MD, Bader GD, Laurenti E, Dick JE. Xie SZ, et al. Among authors: kaufmann kb. Cell Stem Cell. 2019 Nov 7;25(5):639-653.e7. doi: 10.1016/j.stem.2019.09.008. Epub 2019 Oct 17. Cell Stem Cell. 2019. PMID: 31631013 Free PMC article.
A stemness screen reveals C3orf54/INKA1 as a promoter of human leukemia stem cell latency.
Kaufmann KB, Garcia-Prat L, Liu Q, Ng SWK, Takayanagi SI, Mitchell A, Wienholds E, van Galen P, Cumbaa CA, Tsay MJ, Pastrello C, Wagenblast E, Krivdova G, Minden MD, Lechman ER, Zandi S, Jurisica I, Wang JCY, Xie SZ, Dick JE. Kaufmann KB, et al. Blood. 2019 May 16;133(20):2198-2211. doi: 10.1182/blood-2018-10-881441. Epub 2019 Feb 22. Blood. 2019. PMID: 30796022 Free article.
TFEB-mediated endolysosomal activity controls human hematopoietic stem cell fate.
García-Prat L, Kaufmann KB, Schneiter F, Voisin V, Murison A, Chen J, Chan-Seng-Yue M, Gan OI, McLeod JL, Smith SA, Shoong MC, Parris D, Pan K, Zeng AGX, Krivdova G, Gupta K, Takayanagi SI, Wagenblast E, Wang W, Lupien M, Schroeder T, Xie SZ, Dick JE. García-Prat L, et al. Among authors: kaufmann kb. Cell Stem Cell. 2021 Oct 7;28(10):1838-1850.e10. doi: 10.1016/j.stem.2021.07.003. Epub 2021 Aug 2. Cell Stem Cell. 2021. PMID: 34343492 Free article.
miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells.
Lechman ER, Gentner B, Ng SW, Schoof EM, van Galen P, Kennedy JA, Nucera S, Ciceri F, Kaufmann KB, Takayama N, Dobson SM, Trotman-Grant A, Krivdova G, Elzinga J, Mitchell A, Nilsson B, Hermans KG, Eppert K, Marke R, Isserlin R, Voisin V, Bader GD, Zandstra PW, Golub TR, Ebert BL, Lu J, Minden M, Wang JC, Naldini L, Dick JE. Lechman ER, et al. Among authors: kaufmann kb. Cancer Cell. 2016 Feb 8;29(2):214-28. doi: 10.1016/j.ccell.2015.12.011. Epub 2016 Jan 28. Cancer Cell. 2016. PMID: 26832662 Free PMC article.
The Transition from Quiescent to Activated States in Human Hematopoietic Stem Cells Is Governed by Dynamic 3D Genome Reorganization.
Takayama N, Murison A, Takayanagi SI, Arlidge C, Zhou S, Garcia-Prat L, Chan-Seng-Yue M, Zandi S, Gan OI, Boutzen H, Kaufmann KB, Trotman-Grant A, Schoof E, Kron K, Díaz N, Lee JJY, Medina T, De Carvalho DD, Taylor MD, Vaquerizas JM, Xie SZ, Dick JE, Lupien M. Takayama N, et al. Among authors: kaufmann kb. Cell Stem Cell. 2021 Mar 4;28(3):488-501.e10. doi: 10.1016/j.stem.2020.11.001. Epub 2020 Nov 25. Cell Stem Cell. 2021. PMID: 33242413 Free article.
41 results