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Year Number of Results
2003 1
2004 4
2005 1
2006 1
2007 4
2008 9
2009 6
2010 4
2011 7
2012 6
2013 4
2014 9
2015 14
2016 12
2017 7
2018 4
2019 6
2020 6
2021 2
2022 6
2023 1
2024 0

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97 results

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Page 1
Different solubilizing ability of cyclodextrin derivatives for cholesterol in Niemann-Pick disease type C treatment.
Yamada Y, Fukaura-Nishizawa M, Nishiyama A, Ishii A, Kawata T, Shirakawa A, Tanaka M, Kondo Y, Takeo T, Nakagata N, Miwa T, Takeda H, Orita Y, Motoyama K, Higashi T, Arima H, Seki T, Kurauchi Y, Katsuki H, Higaki K, Minami K, Yoshikawa N, Ikeda R, Matsuo M, Irie T, Ishitsuka Y. Yamada Y, et al. Among authors: higaki k. Clin Transl Med. 2023 Aug;13(8):e1350. doi: 10.1002/ctm2.1350. Clin Transl Med. 2023. PMID: 37620691 Free PMC article.
Fine-tuned cholesterol solubilizer, mono-6-O-α-D-maltosyl-γ-cyclodextrin, ameliorates experimental Niemann-Pick disease type C without hearing loss.
Yamada Y, Miwa T, Nakashima M, Shirakawa A, Ishii A, Namba N, Kondo Y, Takeo T, Nakagata N, Motoyama K, Higashi T, Arima H, Kurauchi Y, Seki T, Katsuki H, Okada Y, Ichikawa A, Higaki K, Hayashi K, Minami K, Yoshikawa N, Ikeda R, Ishikawa Y, Kajii T, Tachii K, Takeda H, Orita Y, Matsuo M, Irie T, Ishitsuka Y. Yamada Y, et al. Among authors: higaki k. Biomed Pharmacother. 2022 Nov;155:113698. doi: 10.1016/j.biopha.2022.113698. Epub 2022 Sep 16. Biomed Pharmacother. 2022. PMID: 36116252 Free article.
Development of a Highly Sensitive and Rapid Liquid Chromatography-Tandem Mass Spectrometric Method Using a Basic Mobile Phase Additive to Determine the Characteristics of the Urinary Metabolites for Niemann-Pick Disease Type C.
Maekawa M, Miyoshi K, Narita A, Sato T, Sato Y, Kumondai M, Kikuchi M, Higaki K, Okuyama T, Eto Y, Sakamaki H, Mano N. Maekawa M, et al. Among authors: higaki k. Biol Pharm Bull. 2022;45(9):1259-1268. doi: 10.1248/bpb.b22-00185. Biol Pharm Bull. 2022. PMID: 36047194 Free article.
sp2-Iminosugars targeting human lysosomal β-hexosaminidase as pharmacological chaperone candidates for late-onset Tay-Sachs disease.
González-Cuesta M, Herrera-González I, García-Moreno MI, Ashmus RA, Vocadlo DJ, García Fernández JM, Nanba E, Higaki K, Ortiz Mellet C. González-Cuesta M, et al. Among authors: higaki k. J Enzyme Inhib Med Chem. 2022 Dec;37(1):1364-1374. doi: 10.1080/14756366.2022.2073444. J Enzyme Inhib Med Chem. 2022. PMID: 35575117 Free PMC article.
Differential mode of cholesterol inclusion with 2-hydroxypropyl-cyclodextrins increases safety margin in treatment of Niemann-Pick disease type C.
Yamada Y, Ishitsuka Y, Kondo Y, Nakahara S, Nishiyama A, Takeo T, Nakagata N, Motoyama K, Higashi T, Arima H, Kamei S, Shuto T, Kai H, Hayashino Y, Sugita M, Kikuchi T, Hirata F, Miwa T, Takeda H, Orita Y, Seki T, Ohta T, Kurauchi Y, Katsuki H, Matsuo M, Higaki K, Ohno K, Matsumoto S, Era T, Irie T. Yamada Y, et al. Among authors: higaki k. Br J Pharmacol. 2021 Jul;178(13):2727-2746. doi: 10.1111/bph.15464. Epub 2021 May 12. Br J Pharmacol. 2021. PMID: 33782944 Free article.
Evidence for Urate Uptake Through Monocarboxylate Transporter 9 Expressed in Mammalian Cells and Its Enhancement by Heat Shock.
Otani N, Kurata Y, Maharani N, Kuwabara M, Ikeda N, Notsu T, Li P, Miake J, Yoshida A, Sakaguchi H, Higaki K, Nakasone N, Tsuneto M, Shirayoshi Y, Ouchi M, Ninomiya H, Yamamoto K, Anzai N, Hisatome I. Otani N, et al. Among authors: higaki k. Circ Rep. 2020 Jul 2;2(8):425-432. doi: 10.1253/circrep.CR-20-0016. Circ Rep. 2020. PMID: 33693264 Free PMC article.
Intracerebroventricular Treatment with 2-Hydroxypropyl-β-Cyclodextrin Decreased Cerebellar and Hepatic Glycoprotein Nonmetastatic Melanoma Protein B (GPNMB) Expression in Niemann-Pick Disease Type C Model Mice.
Fukaura M, Ishitsuka Y, Shirakawa S, Ushihama N, Yamada Y, Kondo Y, Takeo T, Nakagata N, Motoyama K, Higashi T, Arima H, Kurauchi Y, Seki T, Katsuki H, Higaki K, Matsuo M, Irie T. Fukaura M, et al. Among authors: higaki k. Int J Mol Sci. 2021 Jan 5;22(1):452. doi: 10.3390/ijms22010452. Int J Mol Sci. 2021. PMID: 33466390 Free PMC article.
97 results