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Biologics (mepolizumab and omalizumab) induced remission in severe asthma patients.
Thomas D, McDonald VM, Stevens S, Harvey ES, Baraket M, Bardin P, Bowden JJ, Bowler S, Chien J, Chung LP, Gillman A, Hew M, Hodge S, James A, Jenkins C, Katelaris CH, Katsoulotos GP, Langton D, Lee J, Marks G, Peters M, Radhakrishna N, Reynolds PN, Rimmer J, Sivakumaran P, Upham JW, Wark P, Yang IA, Gibson PG. Thomas D, et al. Among authors: katsoulotos gp. Allergy. 2024 Feb;79(2):384-392. doi: 10.1111/all.15867. Epub 2023 Aug 25. Allergy. 2024. PMID: 37632144
Biochemical and functional characterization of human transmembrane tryptase (TMT)/tryptase gamma. TMT is an exocytosed mast cell protease that induces airway hyperresponsiveness in vivo via an interleukin-13/interleukin-4 receptor alpha/signal transducer and activator of transcription (STAT) 6-dependent pathway.
Wong GW, Foster PS, Yasuda S, Qi JC, Mahalingam S, Mellor EA, Katsoulotos G, Li L, Boyce JA, Krilis SA, Stevens RL. Wong GW, et al. J Biol Chem. 2002 Nov 1;277(44):41906-15. doi: 10.1074/jbc.M205868200. Epub 2002 Aug 22. J Biol Chem. 2002. PMID: 12194977 Free article.
The Diacylglycerol-dependent translocation of ras guanine nucleotide-releasing protein 4 inside a human mast cell line results in substantial phenotypic changes, including expression of interleukin 13 receptor alpha2.
Katsoulotos GP, Qi M, Qi JC, Tanaka K, Hughes WE, Molloy TJ, Adachi R, Stevens RL, Krilis SA. Katsoulotos GP, et al. J Biol Chem. 2008 Jan 18;283(3):1610-1621. doi: 10.1074/jbc.M707042200. Epub 2007 Nov 16. J Biol Chem. 2008. PMID: 18024961 Free article.
Effectiveness and response predictors of omalizumab in a severe allergic asthma population with a high prevalence of comorbidities: the Australian Xolair Registry.
Gibson PG, Reddel H, McDonald VM, Marks G, Jenkins C, Gillman A, Upham J, Sutherland M, Rimmer J, Thien F, Katsoulotos GP, Cook M, Yang I, Katelaris C, Bowler S, Langton D, Robinson P, Wright C, Yozghatlian V, Burgess S, Sivakumaran P, Jaffe A, Bowden J, Wark PA, Yan KY, Kritikos V, Peters M, Hew M, Aminazad A, Bint M, Guo M. Gibson PG, et al. Among authors: katsoulotos gp. Intern Med J. 2016 Sep;46(9):1054-62. doi: 10.1111/imj.13166. Intern Med J. 2016. PMID: 27350385
Real-life effectiveness of omalizumab in severe allergic asthma above the recommended dosing range criteria.
Hew M, Gillman A, Sutherland M, Wark P, Bowden J, Guo M, Reddel HK, Jenkins C, Marks GB, Thien F, Rimmer J, Katsoulotos GP, Cook M, Yang I, Katelaris C, Bowler S, Langton D, Wright C, Bint M, Yozghatlian V, Burgess S, Sivakumaran P, Yan KY, Kritikos V, Peters M, Baraket M, Aminazad A, Robinson P, Jaffe A, Powell H, Upham JW, McDonald VM, Gibson PG. Hew M, et al. Among authors: katsoulotos gp. Clin Exp Allergy. 2016 Nov;46(11):1407-1415. doi: 10.1111/cea.12774. Epub 2016 Jul 22. Clin Exp Allergy. 2016. PMID: 27377155
Working while unwell: Workplace impairment in people with severe asthma.
Hiles SA, Harvey ES, McDonald VM, Peters M, Bardin P, Reynolds PN, Upham JW, Baraket M, Bhikoo Z, Bowden J, Brockway B, Chung LP, Cochrane B, Foxley G, Garrett J, Hew M, Jayaram L, Jenkins C, Katelaris C, Katsoulotos G, Koh MS, Kritikos V, Lambert M, Langton D, Lara Rivero A, Marks GB, Middleton PG, Nanguzgambo A, Radhakrishna N, Reddel H, Rimmer J, Southcott AM, Sutherland M, Thien F, Wark PAB, Yang IA, Yap E, Gibson PG. Hiles SA, et al. Clin Exp Allergy. 2018 Jun;48(6):650-662. doi: 10.1111/cea.13153. Epub 2018 May 17. Clin Exp Allergy. 2018. PMID: 29676834
Treatable traits can be identified in a severe asthma registry and predict future exacerbations.
McDonald VM, Hiles SA, Godbout K, Harvey ES, Marks GB, Hew M, Peters M, Bardin PG, Reynolds PN, Upham JW, Baraket M, Bhikoo Z, Bowden J, Brockway B, Chung LP, Cochrane B, Foxley G, Garrett J, Jayaram L, Jenkins C, Katelaris C, Katsoulotos G, Koh MS, Kritikos V, Lambert M, Langton D, Lara Rivero A, Middleton PG, Nanguzgambo A, Radhakrishna N, Reddel H, Rimmer J, Southcott AM, Sutherland M, Thien F, Wark PAB, Yang IA, Yap E, Gibson PG. McDonald VM, et al. Respirology. 2019 Jan;24(1):37-47. doi: 10.1111/resp.13389. Epub 2018 Sep 19. Respirology. 2019. PMID: 30230137 Free article.
Severe asthma assessment, management and the organisation of care in Australia and New Zealand: expert forum roundtable meetings.
Maltby S, McDonald VM, Upham JW, Bowler SD, Chung LP, Denton EJ, Fingleton J, Garrett J, Grainge CL, Hew M, James AL, Jenkins C, Katsoulotos G, King GG, Langton D, Marks GB, Menzies-Gow A, Niven RM, Peters M, Reddel HK, Thien F, Thomas PS, Wark PAB, Yap E, Gibson PG; Severe Asthma Expert Forum contributors. Maltby S, et al. Intern Med J. 2021 Feb;51(2):169-180. doi: 10.1111/imj.14806. Intern Med J. 2021. PMID: 32104958 Review.
Mepolizumab effectiveness and identification of super-responders in severe asthma.
Harvey ES, Langton D, Katelaris C, Stevens S, Farah CS, Gillman A, Harrington J, Hew M, Kritikos V, Radhakrishna N, Bardin P, Peters M, Reynolds PN, Upham JW, Baraket M, Bowler S, Bowden J, Chien J, Chung LP, Grainge C, Jenkins C, Katsoulotos GP, Lee J, McDonald VM, Reddel HK, Rimmer J, Wark PAB, Gibson PG. Harvey ES, et al. Among authors: katsoulotos gp. Eur Respir J. 2020 May 21;55(5):1902420. doi: 10.1183/13993003.02420-2019. Print 2020 May. Eur Respir J. 2020. PMID: 32139455 Free article.
29 results