Kati W - Search Results

1

The emerging field of HCV drug resistance.

Koev G, Kati W. Koev G, et al. Among authors: kati w. Expert Opin Investig Drugs. 2008 Mar;17(3):303-19. doi: 10.1517/13543784.17.3.303. Expert Opin Investig Drugs. 2008. PMID: 18321230 Review.

2

Des-A-ring benzothiadiazines: inhibitors of HCV genotype 1 NS5B RNA-dependent RNA polymerase.

Donner PL, Xie Q, Pratt JK, Maring CJ, Kati W, Jiang W, Liu Y, Koev G, Masse S, Montgomery D, Molla A, Kempf DJ. Donner PL, et al. Among authors: kati w. Bioorg Med Chem Lett. 2008 Apr 15;18(8):2735-8. doi: 10.1016/j.bmcl.2008.02.064. Epub 2008 Mar 4. Bioorg Med Chem Lett. 2008. PMID: 18362072

3

Development of a cell-based assay for high-throughput screening of inhibitors against HCV genotypes 1a and 1b in a single well.

Mondal R, Koev G, Pilot-Matias T, He Y, Ng T, Kati W, Molla A. Mondal R, et al. Among authors: kati w. Antiviral Res. 2009 Apr;82(1):82-8. doi: 10.1016/j.antiviral.2008.12.012. Epub 2009 Jan 25. Antiviral Res. 2009. PMID: 19174175

4

High potency improvements to weak aryl uracil HCV polymerase inhibitor leads.

Donner P, Randolph JT, Huang P, Wagner R, Maring C, Lim BH, Colletti L, Liu Y, Mondal R, Beyer J, Koev G, Marsh K, Beno D, Longenecker K, Pilot-Matias T, Kati W, Molla A, Kempf D. Donner P, et al. Among authors: kati w. Bioorg Med Chem Lett. 2013 Aug 1;23(15):4367-9. doi: 10.1016/j.bmcl.2013.05.078. Epub 2013 Jun 4. Bioorg Med Chem Lett. 2013. PMID: 23791079

5

A replicon-based shuttle vector system for assessing the phenotype of HCV NS5B polymerase genes isolated from patient populations.

Middleton T, He Y, Pilot-Matias T, Tripathi R, Lim BH, Roth A, Chen CM, Koev G, Ng TI, Krishnan P, Pithawalla R, Mondal R, Dekhtyar T, Lu L, Mo H, Kati WM, Molla A. Middleton T, et al. J Virol Methods. 2007 Nov;145(2):137-45. doi: 10.1016/j.jviromet.2007.05.016. Epub 2007 Jun 29. J Virol Methods. 2007. PMID: 17604129

6

Synthesis and SAR of novel 1,1-dialkyl-2(1H)-naphthalenones as potent HCV polymerase inhibitors.

Bosse TD, Larson DP, Wagner R, Hutchinson DK, Rockway TW, Kati WM, Liu Y, Masse S, Middleton T, Mo H, Montgomery D, Jiang W, Koev G, Kempf DJ, Molla A. Bosse TD, et al. Among authors: kati wm. Bioorg Med Chem Lett. 2008 Jan 15;18(2):568-70. doi: 10.1016/j.bmcl.2007.11.088. Epub 2007 Nov 28. Bioorg Med Chem Lett. 2008. PMID: 18068361

7

Methods to measure the intracellular concentration of unlabeled compounds within cultured cells using liquid chromatography/tandem mass spectrometry.

Colletti LM, Liu Y, Koev G, Richardson PL, Chen CM, Kati W. Colletti LM, et al. Among authors: kati w. Anal Biochem. 2008 Dec 15;383(2):186-93. doi: 10.1016/j.ab.2008.08.012. Epub 2008 Aug 22. Anal Biochem. 2008. PMID: 18790690

8

In vitro and in vivo antiviral activity and resistance profile of ombitasvir, an inhibitor of hepatitis C virus NS5A.

Krishnan P, Beyer J, Mistry N, Koev G, Reisch T, DeGoey D, Kati W, Campbell A, Williams L, Xie W, Setze C, Molla A, Collins C, Pilot-Matias T. Krishnan P, et al. Among authors: kati w. Antimicrob Agents Chemother. 2015 Feb;59(2):979-87. doi: 10.1128/AAC.04226-14. Epub 2014 Dec 1. Antimicrob Agents Chemother. 2015. PMID: 25451055 Free PMC article.

9

In vitro activity and resistance profile of dasabuvir, a nonnucleoside hepatitis C virus polymerase inhibitor.

Kati W, Koev G, Irvin M, Beyer J, Liu Y, Krishnan P, Reisch T, Mondal R, Wagner R, Molla A, Maring C, Collins C. Kati W, et al. Antimicrob Agents Chemother. 2015 Mar;59(3):1505-11. doi: 10.1128/AAC.04619-14. Epub 2014 Dec 22. Antimicrob Agents Chemother. 2015. PMID: 25534735 Free PMC article.

10

Inhibitors of hepatitis C virus polymerase: synthesis and biological characterization of unsymmetrical dialkyl-hydroxynaphthalenoyl-benzothiadiazines.

Wagner R, Larson DP, Beno DW, Bosse TD, Darbyshire JF, Gao Y, Gates BD, He W, Henry RF, Hernandez LE, Hutchinson DK, Jiang WW, Kati WM, Klein LL, Koev G, Kohlbrenner W, Krueger AC, Liu J, Liu Y, Long MA, Maring CJ, Masse SV, Middleton T, Montgomery DA, Pratt JK, Stuart P, Molla A, Kempf DJ. Wagner R, et al. Among authors: kati wm. J Med Chem. 2009 Mar 26;52(6):1659-69. doi: 10.1021/jm8010965. J Med Chem. 2009. PMID: 19226162

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