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USP47 deubiquitylates Groucho/TLE to promote Wnt-β-catenin signaling.
Kassel S, Hanson AJ, Benchabane H, Saito-Diaz K, Cabel CR, Goldsmith L, Taha M, Kanuganti A, Ng VH, Xu G, Ye F, Picker J, Port F, Boutros M, Weiss VL, Robbins DJ, Thorne CA, Ahmed Y, Lee E. Kassel S, et al. Sci Signal. 2023 Feb 7;16(771):eabn8372. doi: 10.1126/scisignal.abn8372. Epub 2023 Feb 7. Sci Signal. 2023. PMID: 36749823 Free PMC article.
The USP46 deubiquitylase complex increases Wingless/Wnt signaling strength by stabilizing Arrow/LRP6.
Spencer ZT, Ng VH, Benchabane H, Siddiqui GS, Duwadi D, Maines B, Bryant JM, Schwarzkopf A, Yuan K, Kassel SN, Mishra A, Pimentel A, Lebensohn AM, Rohatgi R, Gerber SA, Robbins DJ, Lee E, Ahmed Y. Spencer ZT, et al. Among authors: kassel sn. Nat Commun. 2023 Oct 5;14(1):6174. doi: 10.1038/s41467-023-41843-0. Nat Commun. 2023. PMID: 37798281 Free PMC article.
The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling.
Ng VH, Spencer Z, Neitzel LR, Nayak A, Loberg MA, Shen C, Kassel SN, Kroh HK, An Z, Anthony CC, Bryant JM, Lawson A, Goldsmith L, Benchabane H, Hansen AG, Li J, D'Souza S, Lebensohn AM, Rohatgi R, Weiss WA, Weiss VL, Williams C, Hong CC, Robbins DJ, Ahmed Y, Lee E. Ng VH, et al. Among authors: kassel sn. Nat Commun. 2023 Oct 5;14(1):6173. doi: 10.1038/s41467-023-41836-z. Nat Commun. 2023. PMID: 37798301 Free PMC article.
Genetic Disruption of System xc-Mediated Glutamate Release from Astrocytes Increases Negative-Outcome Behaviors While Preserving Basic Brain Function in Rat.
Hess EM, Kassel SN, Simandl G, Raddatz N, Maunze B, Hurley MM, Grzybowski M, Klotz J, Geurts A, Liu QS, Choi S, Twining RC, Baker DA. Hess EM, et al. Among authors: kassel sn. J Neurosci. 2023 Mar 29;43(13):2349-2361. doi: 10.1523/JNEUROSCI.1525-22.2023. Epub 2023 Feb 14. J Neurosci. 2023. PMID: 36788029 Free PMC article.
An open toolkit for tracking open science partnership implementation and impact.
Gold ER, Ali-Khan SE, Allen L, Ballell L, Barral-Netto M, Carr D, Chalaud D, Chaplin S, Clancy MS, Clarke P, Cook-Deegan R, Dinsmore AP, Doerr M, Federer L, Hill SA, Jacobs N, Jean A, Jefferson OA, Jones C, Kahl LJ, Kariuki TM, Kassel SN, Kiley R, Kittrie ER, Kramer B, Lee WH, MacDonald E, Mangravite LM, Marincola E, Mietchen D, Molloy JC, Namchuk M, Nosek BA, Paquet S, Pirmez C, Seyller A, Skingle M, Spadotto SN, Staniszewska S, Thelwall M. Gold ER, et al. Among authors: kassel sn. Gates Open Res. 2019 Apr 30;3:1442. doi: 10.12688/gatesopenres.12958.2. eCollection 2019. Gates Open Res. 2019. PMID: 31850398 Free PMC article.
Crystal structures of fac-tri-carbonyl-chlorido-(6,6'-dihy-droxy-2,2'-bi-pyridine)-rhenium(I) tetra-hydro-furan monosolvate and fac-bromido-tricarbon-yl(6,6'-dihy-droxy-2,2'-bi-pyridine)-manganese(I) tetra-hydro-furan monosolvate.
Lense S, Piro NA, Kassel SW, Wildish A, Jeffery B. Lense S, et al. Among authors: kassel sw. Acta Crystallogr E Crystallogr Commun. 2016 Jul 29;72(Pt 8):1201-5. doi: 10.1107/S2056989016011841. eCollection 2016 Aug 1. Acta Crystallogr E Crystallogr Commun. 2016. PMID: 27536414 Free PMC article.
Polypharmacology of dopamine receptor ligands.
Butini S, Nikolic K, Kassel S, Brückmann H, Filipic S, Agbaba D, Gemma S, Brogi S, Brindisi M, Campiani G, Stark H. Butini S, et al. Among authors: kassel s. Prog Neurobiol. 2016 Jul;142:68-103. doi: 10.1016/j.pneurobio.2016.03.011. Epub 2016 May 24. Prog Neurobiol. 2016. PMID: 27234980 Review.
32 results