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Inhibition of phosphodiesterase type 9 reduces obesity and cardiometabolic syndrome in mice.
Mishra S, Sadagopan N, Dunkerly-Eyring B, Rodriguez S, Sarver DC, Ceddia RP, Murphy SA, Knutsdottir H, Jani VP, Ashok D, Oeing CU, O'Rourke B, Gangoiti JA, Sears DD, Wong GW, Collins S, Kass DA. Mishra S, et al. Among authors: kass da. J Clin Invest. 2021 Nov 1;131(21):e148798. doi: 10.1172/JCI148798. J Clin Invest. 2021. PMID: 34618683 Free PMC article.
Nitroxyl improves cellular heart function by directly enhancing cardiac sarcoplasmic reticulum Ca2+ cycling.
Tocchetti CG, Wang W, Froehlich JP, Huke S, Aon MA, Wilson GM, Di Benedetto G, O'Rourke B, Gao WD, Wink DA, Toscano JP, Zaccolo M, Bers DM, Valdivia HH, Cheng H, Kass DA, Paolocci N. Tocchetti CG, et al. Among authors: kass da. Circ Res. 2007 Jan 5;100(1):96-104. doi: 10.1161/01.RES.0000253904.53601.c9. Epub 2006 Nov 30. Circ Res. 2007. PMID: 17138943 Free PMC article.
Expression, activity, and pro-hypertrophic effects of PDE5A in cardiac myocytes.
Zhang M, Koitabashi N, Nagayama T, Rambaran R, Feng N, Takimoto E, Koenke T, O'Rourke B, Champion HC, Crow MT, Kass DA. Zhang M, et al. Among authors: kass da. Cell Signal. 2008 Dec;20(12):2231-6. doi: 10.1016/j.cellsig.2008.08.012. Epub 2008 Aug 26. Cell Signal. 2008. PMID: 18790048 Free PMC article.
Regulator of G protein signaling 2 mediates cardiac compensation to pressure overload and antihypertrophic effects of PDE5 inhibition in mice.
Takimoto E, Koitabashi N, Hsu S, Ketner EA, Zhang M, Nagayama T, Bedja D, Gabrielson KL, Blanton R, Siderovski DP, Mendelsohn ME, Kass DA. Takimoto E, et al. Among authors: kass da. J Clin Invest. 2009 Feb;119(2):408-20. doi: 10.1172/JCI35620. Epub 2009 Jan 5. J Clin Invest. 2009. PMID: 19127022 Free PMC article.
484 results