Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

33 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Disrupted CaV1.2 selectivity causes overlapping long QT and Brugada syndrome phenotypes in the CACNA1C-E1115K iPS cell model.
Kashiwa A, Makiyama T, Kohjitani H, Maurissen TL, Ishikawa T, Yamamoto Y, Wuriyanghai Y, Gao J, Huang H, Imamura T, Aizawa T, Nishikawa M, Chonabayashi K, Mishima H, Ohno S, Toyoda F, Sato S, Yoshiura KI, Takahashi K, Yoshida Y, Woltjen K, Horie M, Makita N, Kimura T. Kashiwa A, et al. Heart Rhythm. 2023 Jan;20(1):89-99. doi: 10.1016/j.hrthm.2022.08.021. Epub 2022 Aug 23. Heart Rhythm. 2023. PMID: 36007726
Propranolol Attenuates Late Sodium Current in a Long QT Syndrome Type 3-Human Induced Pluripotent Stem Cell Model.
Hirose S, Makiyama T, Melgari D, Yamamoto Y, Wuriyanghai Y, Yokoi F, Nishiuchi S, Harita T, Hayano M, Kohjitani H, Gao J, Kashiwa A, Nishikawa M, Wu J, Yoshimoto J, Chonabayashi K, Ohno S, Yoshida Y, Horie M, Kimura T. Hirose S, et al. Among authors: kashiwa a. Front Cell Dev Biol. 2020 Aug 13;8:761. doi: 10.3389/fcell.2020.00761. eCollection 2020. Front Cell Dev Biol. 2020. PMID: 32903469 Free PMC article.
Systematic Evaluation of KCNQ1 Variant Using ACMG/AMP Guidelines and Risk Stratification in Long QT Syndrome Type 1.
Kashiwa A, Aiba T, Makimoto H, Shimamoto K, Yamagata K, Kamakura T, Wada M, Miyamoto K, Inoue-Yamada Y, Ishibashi K, Noda T, Nagase S, Miyazaki A, Sakaguchi H, Shiraishi I, Yagihara N, Watanabe H, Aizawa Y, Makiyama T, Itoh H, Hayashi K, Yamagishi M, Sumitomo N, Yoshinaga M, Morita H, Ohe T, Miyamoto Y, Makita N, Yasuda S, Kusano K, Ohno S, Horie M, Shimizu W. Kashiwa A, et al. Circ Genom Precis Med. 2020 Sep 16. doi: 10.1161/CIRCGEN.120.002926. Online ahead of print. Circ Genom Precis Med. 2020. PMID: 32936022 Retracted.
Gradient-based parameter optimization method to determine membrane ionic current composition in human induced pluripotent stem cell-derived cardiomyocytes.
Kohjitani H, Koda S, Himeno Y, Makiyama T, Yamamoto Y, Yoshinaga D, Wuriyanghai Y, Kashiwa A, Toyoda F, Zhang Y, Amano A, Noma A, Kimura T. Kohjitani H, et al. Among authors: kashiwa a. Sci Rep. 2022 Nov 9;12(1):19110. doi: 10.1038/s41598-022-23398-0. Sci Rep. 2022. PMID: 36351955 Free PMC article. Clinical Trial.
Continuous Bayesian variant interpretation accounts for incomplete penetrance among Mendelian cardiac channelopathies.
O'Neill MJ, Sala L, Denjoy I, Wada Y, Kozek K, Crotti L, Dagradi F, Kotta MC, Spazzolini C, Leenhardt A, Salem JE, Kashiwa A, Ohno S, Tao R, Roden DM, Horie M, Extramiana F, Schwartz PJ, Kroncke BM. O'Neill MJ, et al. Among authors: kashiwa a. Genet Med. 2023 Mar;25(3):100355. doi: 10.1016/j.gim.2022.12.002. Epub 2022 Dec 7. Genet Med. 2023. PMID: 36496179 Free PMC article.
Non-missense variants of KCNH2 show better outcomes in type 2 long QT syndrome.
Aizawa T, Wada Y, Hasegawa K, Huang H, Imamura T, Gao J, Kashiwa A, Kohjitani H, Fukuyama M, Kato K, Kato ET, Hisamatsu T, Ohno S, Makiyama T, Kimura T, Horie M. Aizawa T, et al. Among authors: kashiwa a. Europace. 2023 Apr 15;25(4):1491-1499. doi: 10.1093/europace/euac269. Europace. 2023. PMID: 36861347 Free PMC article.
Novel Calmodulin Variant p.E46K Associated With Severe Catecholaminergic Polymorphic Ventricular Tachycardia Produces Robust Arrhythmogenicity in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Gao J, Makiyama T, Yamamoto Y, Kobayashi T, Aoki H, Maurissen TL, Wuriyanghai Y, Kashiwa A, Imamura T, Aizawa T, Huang H, Kohjitani H, Nishikawa M, Chonabayashi K, Fukuyama M, Manabe H, Nakau K, Wada T, Kato K, Toyoda F, Yoshida Y, Makita N, Woltjen K, Ohno S, Kurebayashi N, Murayama T, Sakurai T, Horie M, Kimura T. Gao J, et al. Among authors: kashiwa a. Circ Arrhythm Electrophysiol. 2023 Mar;16(3):e011387. doi: 10.1161/CIRCEP.122.011387. Epub 2023 Mar 3. Circ Arrhythm Electrophysiol. 2023. PMID: 36866681
KUS121, a VCP modulator, has an ameliorating effect on acute and chronic heart failure without calcium loading via maintenance of intracellular ATP levels.
Tsuji S, Otani C, Horie T, Watanabe S, Baba O, Sowa N, Ide Y, Kashiwa A, Makiyama T, Imai H, Nakashima Y, Yamasaki T, Xu S, Matsushita K, Suzuki K, Zou F, Kume E, Hasegawa K, Kimura T, Kakizuka A, Ono K. Tsuji S, et al. Among authors: kashiwa a. Biomed Pharmacother. 2024 Jan;170:115850. doi: 10.1016/j.biopha.2023.115850. Epub 2023 Dec 12. Biomed Pharmacother. 2024. PMID: 38091636 Free article.
33 results