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Dynamic modeling of Nrf2 pathway activation in liver cells after toxicant exposure.
Hiemstra S, Fehling-Kaschek M, Kuijper IA, Bischoff LJM, Wijaya LS, Rosenblatt M, Esselink J, van Egmond A, Mos J, Beltman JB, Timmer J, van de Water B, Kaschek D. Hiemstra S, et al. Among authors: kaschek d. Sci Rep. 2022 May 5;12(1):7336. doi: 10.1038/s41598-022-10857-x. Sci Rep. 2022. PMID: 35513409 Free PMC article.
BlotIt-Optimal alignment of Western blot and qPCR experiments.
Kemmer S, Bang S, Rosenblatt M, Timmer J, Kaschek D. Kemmer S, et al. Among authors: kaschek d. PLoS One. 2022 Aug 10;17(8):e0264295. doi: 10.1371/journal.pone.0264295. eCollection 2022. PLoS One. 2022. PMID: 35947551 Free PMC article.
Model-based identification of TNFα-induced IKKβ-mediated and IκBα-mediated regulation of NFκB signal transduction as a tool to quantify the impact of drug-induced liver injury compounds.
Oppelt A, Kaschek D, Huppelschoten S, Sison-Young R, Zhang F, Buck-Wiese M, Herrmann F, Malkusch S, Krüger CL, Meub M, Merkt B, Zimmermann L, Schofield A, Jones RP, Malik H, Schilling M, Heilemann M, van de Water B, Goldring CE, Park BK, Timmer J, Klingmüller U. Oppelt A, et al. Among authors: kaschek d. NPJ Syst Biol Appl. 2018 Jun 11;4:23. doi: 10.1038/s41540-018-0058-z. eCollection 2018. NPJ Syst Biol Appl. 2018. PMID: 29900006 Free PMC article.
21 results