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Epigenetic Silencing of RIPK3 in Hepatocytes Prevents MLKL-mediated Necroptosis From Contributing to Liver Pathologies.
Preston SP, Stutz MD, Allison CC, Nachbur U, Gouil Q, Tran BM, Duvivier V, Arandjelovic P, Cooney JP, Mackiewicz L, Meng Y, Schaefer J, Bader SM, Peng H, Valaydon Z, Rajasekaran P, Jennison C, Lopaticki S, Farrell A, Ryan M, Howell J, Croagh C, Karunakaran D, Schuster-Klein C, Murphy JM, Fifis T, Christophi C, Vincan E, Blewitt ME, Thompson A, Boddey JA, Doerflinger M, Pellegrini M. Preston SP, et al. Among authors: karunakaran d. Gastroenterology. 2022 Dec;163(6):1643-1657.e14. doi: 10.1053/j.gastro.2022.08.040. Epub 2022 Aug 28. Gastroenterology. 2022. PMID: 36037995 Free article.
RIPK1 Expression Associates With Inflammation in Early Atherosclerosis in Humans and Can Be Therapeutically Silenced to Reduce NF-κB Activation and Atherogenesis in Mice.
Karunakaran D, Nguyen MA, Geoffrion M, Vreeken D, Lister Z, Cheng HS, Otte N, Essebier P, Wyatt H, Kandiah JW, Jung R, Alenghat FJ, Mompeon A, Lee R, Pan C, Gordon E, Rasheed A, Lusis AJ, Liu P, Matic LP, Hedin U, Fish JE, Guo L, Kolodgie F, Virmani R, van Gils JM, Rayner KJ. Karunakaran D, et al. Circulation. 2021 Jan 12;143(2):163-177. doi: 10.1161/CIRCULATIONAHA.118.038379. Epub 2020 Nov 23. Circulation. 2021. PMID: 33222501
Macrophage Mitochondrial Energy Status Regulates Cholesterol Efflux and Is Enhanced by Anti-miR33 in Atherosclerosis.
Karunakaran D, Thrush AB, Nguyen MA, Richards L, Geoffrion M, Singaravelu R, Ramphos E, Shangari P, Ouimet M, Pezacki JP, Moore KJ, Perisic L, Maegdefessel L, Hedin U, Harper ME, Rayner KJ. Karunakaran D, et al. Circ Res. 2015 Jul 17;117(3):266-78. doi: 10.1161/CIRCRESAHA.117.305624. Epub 2015 May 22. Circ Res. 2015. PMID: 26002865 Free PMC article.
RIPK1 gene variants associate with obesity in humans and can be therapeutically silenced to reduce obesity in mice.
Karunakaran D, Turner AW, Duchez AC, Soubeyrand S, Rasheed A, Smyth D, Cook DP, Nikpay M, Kandiah JW, Pan C, Geoffrion M, Lee R, Boytard L, Wyatt H, Nguyen MA, Lau P, Laakso M, Ramkhelawon B, Alvarez M, Pietiläinen KH, Pajukanta P, Vanderhyden BC, Liu P, Berger SB, Gough PJ, Bertin J, Harper ME, Lusis AJ, McPherson R, Rayner KJ. Karunakaran D, et al. Nat Metab. 2020 Oct;2(10):1113-1125. doi: 10.1038/s42255-020-00279-2. Epub 2020 Sep 28. Nat Metab. 2020. PMID: 32989316 Free PMC article.
Macrophage miRNAs in atherosclerosis.
Karunakaran D, Rayner KJ. Karunakaran D, et al. Biochim Biophys Acta. 2016 Dec;1861(12 Pt B):2087-2093. doi: 10.1016/j.bbalip.2016.02.006. Epub 2016 Feb 18. Biochim Biophys Acta. 2016. PMID: 26899196 Review.
Publisher Correction: RIPK1 gene variants associate with obesity in humans and can be therapeutically silenced to reduce obesity in mice.
Karunakaran D, Turner AW, Duchez AC, Soubeyrand S, Rasheed A, Smyth D, Cook DP, Nikpay M, Kandiah JW, Pan C, Geoffrion M, Lee R, Boytard L, Wyatt H, Nguyen MA, Lau P, Laakso M, Ramkhelawon B, Alvarez M, Pietiläinen KH, Pajukanta P, Vanderhyden BC, Liu P, Berger SB, Gough PJ, Bertin J, Harper ME, Lusis AJ, McPherson R, Rayner KJ. Karunakaran D, et al. Nat Metab. 2020 Oct;2(10):1181. doi: 10.1038/s42255-020-00309-z. Nat Metab. 2020. PMID: 33033401
62 results