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Widespread macromolecular interaction perturbations in human genetic disorders.
Sahni N, Yi S, Taipale M, Fuxman Bass JI, Coulombe-Huntington J, Yang F, Peng J, Weile J, Karras GI, Wang Y, Kovács IA, Kamburov A, Krykbaeva I, Lam MH, Tucker G, Khurana V, Sharma A, Liu YY, Yachie N, Zhong Q, Shen Y, Palagi A, San-Miguel A, Fan C, Balcha D, Dricot A, Jordan DM, Walsh JM, Shah AA, Yang X, Stoyanova AK, Leighton A, Calderwood MA, Jacob Y, Cusick ME, Salehi-Ashtiani K, Whitesell LJ, Sunyaev S, Berger B, Barabási AL, Charloteaux B, Hill DE, Hao T, Roth FP, Xia Y, Walhout AJM, Lindquist S, Vidal M. Sahni N, et al. Among authors: karras gi. Cell. 2015 Apr 23;161(3):647-660. doi: 10.1016/j.cell.2015.04.013. Cell. 2015. PMID: 25910212 Free PMC article.
HSP90 Shapes the Consequences of Human Genetic Variation.
Karras GI, Yi S, Sahni N, Fischer M, Xie J, Vidal M, D'Andrea AD, Whitesell L, Lindquist S. Karras GI, et al. Cell. 2017 Feb 23;168(5):856-866.e12. doi: 10.1016/j.cell.2017.01.023. Epub 2017 Feb 16. Cell. 2017. PMID: 28215707 Free PMC article.
Role of HSP90 in the Regulation of de Novo Purine Biosynthesis.
Pedley AM, Karras GI, Zhang X, Lindquist S, Benkovic SJ. Pedley AM, et al. Among authors: karras gi. Biochemistry. 2018 Jun 12;57(23):3217-3221. doi: 10.1021/acs.biochem.8b00140. Epub 2018 Mar 23. Biochemistry. 2018. PMID: 29553718 Free PMC article.
Regulation of double-stranded DNA gap repair by the RAD6 pathway.
Moertl S, Karras GI, Wismüller T, Ahne F, Eckardt-Schupp F. Moertl S, et al. Among authors: karras gi. DNA Repair (Amst). 2008 Nov 1;7(11):1893-906. doi: 10.1016/j.dnarep.2008.07.016. Epub 2008 Sep 11. DNA Repair (Amst). 2008. PMID: 18722556
The macro domain is an ADP-ribose binding module.
Karras GI, Kustatscher G, Buhecha HR, Allen MD, Pugieux C, Sait F, Bycroft M, Ladurner AG. Karras GI, et al. EMBO J. 2005 Jun 1;24(11):1911-20. doi: 10.1038/sj.emboj.7600664. Epub 2005 May 19. EMBO J. 2005. PMID: 15902274 Free PMC article.
15 results