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Discovery and Preclinical Pharmacology of NX-2127, an Orally Bioavailable Degrader of Bruton's Tyrosine Kinase with Immunomodulatory Activity for the Treatment of Patients with B Cell Malignancies.
Robbins DW, Noviski MA, Tan YS, Konst ZA, Kelly A, Auger P, Brathaban N, Cass R, Chan ML, Cherala G, Clifton MC, Gajewski S, Ingallinera TG, Karr D, Kato D, Ma J, McKinnell J, McIntosh J, Mihalic J, Murphy B, Panga JR, Peng G, Powers J, Perez L, Rountree R, Tenn-McClellan A, Sands AT, Weiss DR, Wu J, Ye J, Guiducci C, Hansen G, Cohen F. Robbins DW, et al. Among authors: karr d. J Med Chem. 2024 Feb 22;67(4):2321-2336. doi: 10.1021/acs.jmedchem.3c01007. Epub 2024 Feb 1. J Med Chem. 2024. PMID: 38300987
Discovery of Reversible Covalent Bruton's Tyrosine Kinase Inhibitors PRN473 and PRN1008 (Rilzabrutinib).
Owens TD, Brameld KA, Verner EJ, Ton T, Li X, Zhu J, Masjedizadeh MR, Bradshaw JM, Hill RJ, Tam D, Bisconte A, Kim EO, Francesco M, Xing Y, Shu J, Karr D, LaStant J, Finkle D, Loewenstein N, Haberstock-Debic H, Taylor MJ, Nunn P, Langrish CL, Goldstein DM. Owens TD, et al. Among authors: karr d. J Med Chem. 2022 Apr 14;65(7):5300-5316. doi: 10.1021/acs.jmedchem.1c01170. Epub 2022 Mar 18. J Med Chem. 2022. PMID: 35302767
Visual Acuity and Ophthalmic Outcomes 5 Years After Cataract Surgery Among Children Younger Than 13 Years.
Repka MX, Dean TW, Kraker RT, Li Z, Yen KG, de Alba Campomanes AG, Young MP, Rahmani B, Haider KM, Whitehead GF, Lambert SR, Kurup SP, Kraus CL, Cotter SA, Holmes JM; Pediatric Eye Disease Investigator Group. Repka MX, et al. JAMA Ophthalmol. 2022 Mar 1;140(3):269-276. doi: 10.1001/jamaophthalmol.2021.6176. JAMA Ophthalmol. 2022. PMID: 35142808 Free PMC article.
Visual Outcomes and Complications After Lensectomy for Traumatic Cataract in Children.
Writing Committee for the Pediatric Eye Disease Investigator Group (PEDIG); Bothun ED, Repka MX, Dean TW, Gray ME, Lenhart PD, Li Z, Morrison DG, Wallace DK, Kraker RT, Cotter SA, Holmes JM. Writing Committee for the Pediatric Eye Disease Investigator Group (PEDIG), et al. JAMA Ophthalmol. 2021 Jun 1;139(6):647-653. doi: 10.1001/jamaophthalmol.2021.0980. JAMA Ophthalmol. 2021. PMID: 33956055 Free PMC article.
Screening Examination of Premature Infants for Retinopathy of Prematurity.
Fierson WM; AMERICAN ACADEMY OF PEDIATRICS Section on Ophthalmology; AMERICAN ACADEMY OF OPHTHALMOLOGY; AMERICAN ASSOCIATION FOR PEDIATRIC OPHTHALMOLOGY AND STRABISMUS; AMERICAN ASSOCIATION OF CERTIFIED ORTHOPTISTS. Fierson WM, et al. Pediatrics. 2018 Dec;142(6):e20183061. doi: 10.1542/peds.2018-3061. Pediatrics. 2018. PMID: 30478242 Review.
92 results