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In vivo suppression of vein graft disease by nonviral, electroporation-mediated, gene transfer of tissue inhibitor of metalloproteinase-1 linked to the amino terminal fragment of urokinase (TIMP-1.ATF), a cell-surface directed matrix metalloproteinase inhibitor.
Eefting D, de Vries MR, Grimbergen JM, Karper JC, van Bockel JH, Quax PH. Eefting D, et al. Among authors: karper jc. J Vasc Surg. 2010 Feb;51(2):429-37. doi: 10.1016/j.jvs.2009.09.026. Epub 2009 Dec 24. J Vasc Surg. 2010. PMID: 20036101 Free article.
Blocking toll-like receptors 7 and 9 reduces postinterventional remodeling via reduced macrophage activation, foam cell formation, and migration.
Karper JC, Ewing MM, Habets KL, de Vries MR, Peters EA, van Oeveren-Rietdijk AM, de Boer HC, Hamming JF, Kuiper J, Kandimalla ER, La Monica N, Jukema JW, Quax PH. Karper JC, et al. Arterioscler Thromb Vasc Biol. 2012 Aug;32(8):e72-80. doi: 10.1161/ATVBAHA.112.249391. Epub 2012 May 24. Arterioscler Thromb Vasc Biol. 2012. PMID: 22628437
An unexpected intriguing effect of Toll-like receptor regulator RP105 (CD180) on atherosclerosis formation with alterations on B-cell activation.
Karper JC, de Jager SC, Ewing MM, de Vries MR, Bot I, van Santbrink PJ, Redeker A, Mallat Z, Binder CJ, Arens R, Jukema JW, Kuiper J, Quax PH. Karper JC, et al. Arterioscler Thromb Vasc Biol. 2013 Dec;33(12):2810-7. doi: 10.1161/ATVBAHA.113.301882. Epub 2013 Oct 10. Arterioscler Thromb Vasc Biol. 2013. PMID: 24115036
28 results