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The balancing act of NEET proteins: Iron, ROS, calcium and metabolism.
Nechushtai R, Karmi O, Zuo K, Marjault HB, Darash-Yahana M, Sohn YS, King SD, Zandalinas SI, Carloni P, Mittler R. Nechushtai R, et al. Among authors: karmi o. Biochim Biophys Acta Mol Cell Res. 2020 Nov;1867(11):118805. doi: 10.1016/j.bbamcr.2020.118805. Epub 2020 Aug 1. Biochim Biophys Acta Mol Cell Res. 2020. PMID: 32745723 Free article. Review.
Activation of apoptosis in NAF-1-deficient human epithelial breast cancer cells.
Holt SH, Darash-Yahana M, Sohn YS, Song L, Karmi O, Tamir S, Michaeli D, Luo Y, Paddock ML, Jennings PA, Onuchic JN, Azad RK, Pikarsky E, Cabantchik IZ, Nechushtai R, Mittler R. Holt SH, et al. Among authors: karmi o. J Cell Sci. 2016 Jan 1;129(1):155-65. doi: 10.1242/jcs.178293. Epub 2015 Nov 30. J Cell Sci. 2016. PMID: 26621032 Free PMC article.
GLP-1-RA Corrects Mitochondrial Labile Iron Accumulation and Improves β-Cell Function in Type 2 Wolfram Syndrome.
Danielpur L, Sohn YS, Karmi O, Fogel C, Zinger A, Abu-Libdeh A, Israeli T, Riahi Y, Pappo O, Birk R, Zangen DH, Mittler R, Cabantchik ZI, Cerasi E, Nechushtai R, Leibowitz G. Danielpur L, et al. Among authors: karmi o. J Clin Endocrinol Metab. 2016 Oct;101(10):3592-3599. doi: 10.1210/jc.2016-2240. Epub 2016 Jul 26. J Clin Endocrinol Metab. 2016. PMID: 27459537
Breast cancer tumorigenicity is dependent on high expression levels of NAF-1 and the lability of its Fe-S clusters.
Darash-Yahana M, Pozniak Y, Lu M, Sohn YS, Karmi O, Tamir S, Bai F, Song L, Jennings PA, Pikarsky E, Geiger T, Onuchic JN, Mittler R, Nechushtai R. Darash-Yahana M, et al. Among authors: karmi o. Proc Natl Acad Sci U S A. 2016 Sep 27;113(39):10890-5. doi: 10.1073/pnas.1612736113. Epub 2016 Sep 12. Proc Natl Acad Sci U S A. 2016. PMID: 27621439 Free PMC article.
Interactions between mitoNEET and NAF-1 in cells.
Karmi O, Holt SH, Song L, Tamir S, Luo Y, Bai F, Adenwalla A, Darash-Yahana M, Sohn YS, Jennings PA, Azad RK, Onuchic JN, Morcos F, Nechushtai R, Mittler R. Karmi O, et al. PLoS One. 2017 Apr 20;12(4):e0175796. doi: 10.1371/journal.pone.0175796. eCollection 2017. PLoS One. 2017. PMID: 28426722 Free PMC article.
Structure of the human monomeric NEET protein MiNT and its role in regulating iron and reactive oxygen species in cancer cells.
Lipper CH, Karmi O, Sohn YS, Darash-Yahana M, Lammert H, Song L, Liu A, Mittler R, Nechushtai R, Onuchic JN, Jennings PA. Lipper CH, et al. Among authors: karmi o. Proc Natl Acad Sci U S A. 2018 Jan 9;115(2):272-277. doi: 10.1073/pnas.1715842115. Epub 2017 Dec 19. Proc Natl Acad Sci U S A. 2018. PMID: 29259115 Free PMC article.
The anti-apoptotic proteins NAF-1 and iASPP interact to drive apoptosis in cancer cells.
Iosub-Amir A, Bai F, Sohn YS, Song L, Tamir S, Marjault HB, Mayer G, Karmi O, Jennings PA, Mittler R, Onuchic JN, Friedler A, Nechushtai R. Iosub-Amir A, et al. Among authors: karmi o. Chem Sci. 2018 Nov 20;10(3):665-673. doi: 10.1039/c8sc03390k. eCollection 2019 Jan 21. Chem Sci. 2018. PMID: 30774867 Free PMC article.
Chemical targeting of NEET proteins reveals their function in mitochondrial morphodynamics.
Molino D, Pila-Castellanos I, Marjault HB, Dias Amoedo N, Kopp K, Rochin L, Karmi O, Sohn YS, Lines L, Hamaï A, Joly S, Radreau P, Vonderscher J, Codogno P, Giordano F, Machin P, Rossignol R, Meldrum E, Arnoult D, Ruggieri A, Nechushtai R, de Chassey B, Morel E. Molino D, et al. Among authors: karmi o. EMBO Rep. 2020 Dec 3;21(12):e49019. doi: 10.15252/embr.201949019. Epub 2020 Nov 12. EMBO Rep. 2020. PMID: 33180995 Free PMC article.
23 results