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FPR2 Shapes an Immune-Excluded Pancreatic Tumor Microenvironment and Drives T-cell Exhaustion in a Sex-Dependent Manner.
He F, Tay AHM, Calandigary A, Malki E, Suzuki S, Liu T, Wang Q, Fernández-Moro C, Kaisso M, Olofsson-Sahl P, Melssen M, Sze SK, Björnstedt M, Löhr MJ, Karlsson MCI, Heuchel R, Sarhan D. He F, et al. Among authors: karlsson mci. Cancer Res. 2023 May 15;83(10):1628-1645. doi: 10.1158/0008-5472.CAN-22-2932. Cancer Res. 2023. PMID: 36919330
Targeting a scavenger receptor on tumor-associated macrophages activates tumor cell killing by natural killer cells.
Eisinger S, Sarhan D, Boura VF, Ibarlucea-Benitez I, Tyystjärvi S, Oliynyk G, Arsenian-Henriksson M, Lane D, Wikström SL, Kiessling R, Virgilio T, Gonzalez SF, Kaczynska D, Kanatani S, Daskalaki E, Wheelock CE, Sedimbi S, Chambers BJ, Ravetch JV, Karlsson MCI. Eisinger S, et al. Among authors: karlsson mci. Proc Natl Acad Sci U S A. 2020 Dec 15;117(50):32005-32016. doi: 10.1073/pnas.2015343117. Epub 2020 Nov 23. Proc Natl Acad Sci U S A. 2020. PMID: 33229588 Free PMC article.
Distinct developmental pathways from blood monocytes generate human lung macrophage diversity.
Evren E, Ringqvist E, Tripathi KP, Sleiers N, Rives IC, Alisjahbana A, Gao Y, Sarhan D, Halle T, Sorini C, Lepzien R, Marquardt N, Michaëlsson J, Smed-Sörensen A, Botling J, Karlsson MCI, Villablanca EJ, Willinger T. Evren E, et al. Among authors: karlsson mci. Immunity. 2021 Feb 9;54(2):259-275.e7. doi: 10.1016/j.immuni.2020.12.003. Epub 2020 Dec 30. Immunity. 2021. PMID: 33382972 Free article.
Targeting myeloid suppressive cells revives cytotoxic anti-tumor responses in pancreatic cancer.
Sarhan D, Eisinger S, He F, Bergsland M, Pelicano C, Driescher C, Westberg K, Benitez II, Humoud R, Palano G, Li S, Carannante V, Muhr J, Önfelt B, Schlisio S, Ravetch JV, Heuchel R, Löhr MJ, Karlsson MCI. Sarhan D, et al. Among authors: karlsson mci. iScience. 2022 Oct 9;25(11):105317. doi: 10.1016/j.isci.2022.105317. eCollection 2022 Nov 18. iScience. 2022. PMID: 36310582 Free PMC article.
The MDM2 Inhibitor Navtemadlin Arrests Mouse Melanoma Growth In Vivo and Potentiates Radiotherapy.
Ingelshed K, Spiegelberg D, Kannan P, Påvénius L, Hacheney J, Jiang L, Eisinger S, Lianoudaki D, Lama D, Castillo F, Bosdotter C, Kretzschmar WW, Al-Radi O, Fritz N, Villablanca EJ, Karlsson MCI, Wermeling F, Nestor M, Lane DP, Sedimbi SK. Ingelshed K, et al. Among authors: karlsson mci. Cancer Res Commun. 2022 Sep 28;2(9):1075-1088. doi: 10.1158/2767-9764.CRC-22-0053. eCollection 2022 Sep. Cancer Res Commun. 2022. PMID: 36922937 Free PMC article.
Expression of scavenger receptor MARCO defines a targetable tumor-associated macrophage subset in non-small cell lung cancer.
La Fleur L, Boura VF, Alexeyenko A, Berglund A, Pontén V, Mattsson JSM, Djureinovic D, Persson J, Brunnström H, Isaksson J, Brandén E, Koyi H, Micke P, Karlsson MCI, Botling J. La Fleur L, et al. Among authors: karlsson mci. Int J Cancer. 2018 Oct 1;143(7):1741-1752. doi: 10.1002/ijc.31545. Epub 2018 May 13. Int J Cancer. 2018. PMID: 29667169 Free article.
87 results