Karlberg T - Search Results

1

Structural basis for the interaction between tankyrase-2 and a potent Wnt-signaling inhibitor.

Karlberg T, Markova N, Johansson I, Hammarström M, Schütz P, Weigelt J, Schüler H. Karlberg T, et al. J Med Chem. 2010 Jul 22;53(14):5352-5. doi: 10.1021/jm100249w. J Med Chem. 2010. PMID: 20565110

2

Zinc binding catalytic domain of human tankyrase 1.

Lehtiö L, Collins R, van den Berg S, Johansson A, Dahlgren LG, Hammarström M, Helleday T, Holmberg-Schiavone L, Karlberg T, Weigelt J. Lehtiö L, et al. Among authors: karlberg t. J Mol Biol. 2008 May 23;379(1):136-45. doi: 10.1016/j.jmb.2008.03.058. Epub 2008 Apr 3. J Mol Biol. 2008. PMID: 18436240

3

The DEXD/H-box RNA helicase DDX19 is regulated by an {alpha}-helical switch.

Collins R, Karlberg T, Lehtiö L, Schütz P, van den Berg S, Dahlgren LG, Hammarström M, Weigelt J, Schüler H. Collins R, et al. Among authors: karlberg t. J Biol Chem. 2009 Apr 17;284(16):10296-300. doi: 10.1074/jbc.C900018200. Epub 2009 Feb 25. J Biol Chem. 2009. PMID: 19244245 Free PMC article.

4

Structural basis for inhibitor specificity in human poly(ADP-ribose) polymerase-3.

Lehtiö L, Jemth AS, Collins R, Loseva O, Johansson A, Markova N, Hammarström M, Flores A, Holmberg-Schiavone L, Weigelt J, Helleday T, Schüler H, Karlberg T. Lehtiö L, et al. Among authors: karlberg t. J Med Chem. 2009 May 14;52(9):3108-11. doi: 10.1021/jm900052j. J Med Chem. 2009. PMID: 19354255

5

Crystal structure of the catalytic domain of human PARP2 in complex with PARP inhibitor ABT-888.

Karlberg T, Hammarström M, Schütz P, Svensson L, Schüler H. Karlberg T, et al. Biochemistry. 2010 Feb 16;49(6):1056-8. doi: 10.1021/bi902079y. Biochemistry. 2010. PMID: 20092359

6

Crystal structure of human RNA helicase A (DHX9): structural basis for unselective nucleotide base binding in a DEAD-box variant protein.

Schütz P, Wahlberg E, Karlberg T, Hammarström M, Collins R, Flores A, Schüler H. Schütz P, et al. Among authors: karlberg t. J Mol Biol. 2010 Jul 23;400(4):768-82. doi: 10.1016/j.jmb.2010.05.046. Epub 2010 May 25. J Mol Biol. 2010. PMID: 20510246

7

Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors.

Wahlberg E, Karlberg T, Kouznetsova E, Markova N, Macchiarulo A, Thorsell AG, Pol E, Frostell Å, Ekblad T, Öncü D, Kull B, Robertson GM, Pellicciari R, Schüler H, Weigelt J. Wahlberg E, et al. Among authors: karlberg t. Nat Biotechnol. 2012 Feb 19;30(3):283-8. doi: 10.1038/nbt.2121. Nat Biotechnol. 2012. PMID: 22343925

8

Crystal structure of human ADP-ribose transferase ARTD15/PARP16 reveals a novel putative regulatory domain.

Karlberg T, Thorsell AG, Kallas Å, Schüler H. Karlberg T, et al. J Biol Chem. 2012 Jul 13;287(29):24077-81. doi: 10.1074/jbc.M112.379289. Epub 2012 Jun 1. J Biol Chem. 2012. PMID: 22661712 Free PMC article.

9

Crystal structure of the ATPase domain of the human AAA+ protein paraplegin/SPG7.

Karlberg T, van den Berg S, Hammarström M, Sagemark J, Johansson I, Holmberg-Schiavone L, Schüler H. Karlberg T, et al. PLoS One. 2009 Oct 20;4(10):e6975. doi: 10.1371/journal.pone.0006975. PLoS One. 2009. PMID: 19841671 Free PMC article.

10

PARP-3 is a mono-ADP-ribosylase that activates PARP-1 in the absence of DNA.

Loseva O, Jemth AS, Bryant HE, Schüler H, Lehtiö L, Karlberg T, Helleday T. Loseva O, et al. Among authors: karlberg t. J Biol Chem. 2010 Mar 12;285(11):8054-60. doi: 10.1074/jbc.M109.077834. Epub 2010 Jan 11. J Biol Chem. 2010. PMID: 20064938 Free PMC article.

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