Karl N - Search Results

1

The rocaglate CR-31-B (-) inhibits SARS-CoV-2 replication at non-cytotoxic, low nanomolar concentrations in vitro and ex vivo.

Müller C, Obermann W, Karl N, Wendel HG, Taroncher-Oldenburg G, Pleschka S, Hartmann RK, Grünweller A, Ziebuhr J. Müller C, et al. Among authors: karl n. Antiviral Res. 2021 Feb;186:105012. doi: 10.1016/j.antiviral.2021.105012. Epub 2021 Jan 8. Antiviral Res. 2021. PMID: 33422611 Free PMC article.

2

Human coronavirus 229E papain-like proteases have overlapping specificities but distinct functions in viral replication.

Ziebuhr J, Schelle B, Karl N, Minskaia E, Bayer S, Siddell SG, Gorbalenya AE, Thiel V. Ziebuhr J, et al. Among authors: karl n. J Virol. 2007 Apr;81(8):3922-32. doi: 10.1128/JVI.02091-06. Epub 2007 Jan 24. J Virol. 2007. PMID: 17251282 Free PMC article.

3

Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication.

Kindler E, Gil-Cruz C, Spanier J, Li Y, Wilhelm J, Rabouw HH, Züst R, Hwang M, V'kovski P, Stalder H, Marti S, Habjan M, Cervantes-Barragan L, Elliot R, Karl N, Gaughan C, van Kuppeveld FJ, Silverman RH, Keller M, Ludewig B, Bergmann CC, Ziebuhr J, Weiss SR, Kalinke U, Thiel V. Kindler E, et al. Among authors: karl n. PLoS Pathog. 2017 Feb 3;13(2):e1006195. doi: 10.1371/journal.ppat.1006195. eCollection 2017 Feb. PLoS Pathog. 2017. PMID: 28158275 Free PMC article.

4

The NF-κB-dependent and -independent transcriptome and chromatin landscapes of human coronavirus 229E-infected cells.

Poppe M, Wittig S, Jurida L, Bartkuhn M, Wilhelm J, Müller H, Beuerlein K, Karl N, Bhuju S, Ziebuhr J, Schmitz ML, Kracht M. Poppe M, et al. Among authors: karl n. PLoS Pathog. 2017 Mar 29;13(3):e1006286. doi: 10.1371/journal.ppat.1006286. eCollection 2017 Mar. PLoS Pathog. 2017. PMID: 28355270 Free PMC article.

5

Structural and functional conservation of cis-acting RNA elements in coronavirus 5'-terminal genome regions.

Madhugiri R, Karl N, Petersen D, Lamkiewicz K, Fricke M, Wend U, Scheuer R, Marz M, Ziebuhr J. Madhugiri R, et al. Among authors: karl n. Virology. 2018 Apr;517:44-55. doi: 10.1016/j.virol.2017.11.025. Epub 2017 Dec 6. Virology. 2018. PMID: 29223446 Free PMC article.

6

Characterization of a bafinivirus exoribonuclease activity.

Durzynska I, Sauerwald M, Karl N, Madhugiri R, Ziebuhr J. Durzynska I, et al. Among authors: karl n. J Gen Virol. 2018 Sep;99(9):1253-1260. doi: 10.1099/jgv.0.001120. Epub 2018 Jul 30. J Gen Virol. 2018. PMID: 30058998

7

Identification and Characterization of a Human Coronavirus 229E Nonstructural Protein 8-Associated RNA 3'-Terminal Adenylyltransferase Activity.

Tvarogová J, Madhugiri R, Bylapudi G, Ferguson LJ, Karl N, Ziebuhr J. Tvarogová J, et al. Among authors: karl n. J Virol. 2019 May 29;93(12):e00291-19. doi: 10.1128/JVI.00291-19. Print 2019 Jun 15. J Virol. 2019. PMID: 30918070 Free PMC article.

8

Coronavirus replication-transcription complex: Vital and selective NMPylation of a conserved site in nsp9 by the NiRAN-RdRp subunit.

Slanina H, Madhugiri R, Bylapudi G, Schultheiß K, Karl N, Gulyaeva A, Gorbalenya AE, Linne U, Ziebuhr J. Slanina H, et al. Among authors: karl n. Proc Natl Acad Sci U S A. 2021 Feb 9;118(6):e2022310118. doi: 10.1073/pnas.2022310118. Proc Natl Acad Sci U S A. 2021. PMID: 33472860 Free PMC article.

9

Multi-level inhibition of coronavirus replication by chemical ER stress.

Shaban MS, Müller C, Mayr-Buro C, Weiser H, Meier-Soelch J, Albert BV, Weber A, Linne U, Hain T, Babayev I, Karl N, Hofmann N, Becker S, Herold S, Schmitz ML, Ziebuhr J, Kracht M. Shaban MS, et al. Among authors: karl n. Nat Commun. 2021 Sep 20;12(1):5536. doi: 10.1038/s41467-021-25551-1. Nat Commun. 2021. PMID: 34545074 Free PMC article.

10

Conserved Characteristics of NMPylation Activities of Alpha- and Betacoronavirus NiRAN Domains.

Slanina H, Madhugiri R, Wenk K, Reinke T, Schultheiß K, Schultheis J, Karl N, Linne U, Ziebuhr J. Slanina H, et al. Among authors: karl n. J Virol. 2023 Jun 29;97(6):e0046523. doi: 10.1128/jvi.00465-23. Epub 2023 May 18. J Virol. 2023. PMID: 37199624 Free PMC article.

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