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Curcumin derivative 1, 2-bis [(3E, 5E)-3, 5-bis [(2-chlorophenyl) methylene]-4-oxo-1-piperidyl] ethane-1, 2-dione (ST03) induces mitochondria mediated apoptosis in ovarian cancer cells and inhibits tumor progression in EAC mouse model.
Koroth J, Mahadeva R, Ravindran F, Parashar TR, Teja V, Karki SS, Choudhary B. Koroth J, et al. Among authors: karki ss. Transl Oncol. 2022 Jan;15(1):101280. doi: 10.1016/j.tranon.2021.101280. Epub 2021 Nov 19. Transl Oncol. 2022. PMID: 34801859 Free PMC article.
Identification and characterization of novel ligase I inhibitors.
Pandey M, Kumar S, Goldsmith G, Srivastava M, Elango S, Shameem M, Bannerjee D, Choudhary B, Karki SS, Raghavan SC. Pandey M, et al. Among authors: karki ss. Mol Carcinog. 2017 Feb;56(2):550-566. doi: 10.1002/mc.22516. Epub 2016 Jun 27. Mol Carcinog. 2017. PMID: 27312791
Novel BCL2 inhibitor, Disarib induces apoptosis by disruption of BCL2-BAK interaction.
Vartak SV, Iyer D, Santhoshkumar TR, Sharma S, Mishra A, Goldsmith G, Srivastava M, Srivastava S, Karki SS, Surolia A, Choudhary B, Raghavan SC. Vartak SV, et al. Among authors: karki ss. Biochem Pharmacol. 2017 May 1;131:16-28. doi: 10.1016/j.bcp.2017.02.015. Epub 2017 Feb 20. Biochem Pharmacol. 2017. PMID: 28223017
Autocyclized and oxidized forms of SCR7 induce cancer cell death by inhibiting nonhomologous DNA end joining in a Ligase IV dependent manner.
Vartak SV, Swarup HA, Gopalakrishnan V, Gopinatha VK, Ropars V, Nambiar M, John F, Kothanahally SKS, Kumari R, Kumari N, Ray U, Radha G, Dinesh D, Pandey M, Ananda H, Karki SS, Srivastava M, Charbonnier JB, Choudhary B, Mantelingu K, Raghavan SC. Vartak SV, et al. Among authors: karki ss. FEBS J. 2018 Nov;285(21):3959-3976. doi: 10.1111/febs.14661. Epub 2018 Oct 8. FEBS J. 2018. PMID: 30230716 Free article.
Effects of green synthesised silver nanoparticles (ST06-AgNPs) using curcumin derivative (ST06) on human cervical cancer cells (HeLa) in vitro and EAC tumor bearing mice models.
Murugesan K, Koroth J, Srinivasan PP, Singh A, Mukundan S, Karki SS, Choudhary B, Gupta CM. Murugesan K, et al. Among authors: karki ss. Int J Nanomedicine. 2019 Jul 16;14:5257-5270. doi: 10.2147/IJN.S202404. eCollection 2019. Int J Nanomedicine. 2019. PMID: 31409988 Free PMC article. Retracted.
46 results