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Production of lentiviral vectors using novel, enzymatically produced, linear DNA.
Gene Ther. 2019 Apr;26(3-4):86-92. doi: 10.1038/s41434-018-0056-1. Epub 2019 Jan 14.
Gene Ther. 2019.
PMID: 30643205
Free PMC article.
Linear doggybone DNA vaccine induces similar immunological responses to conventional plasmid DNA independently of immune recognition by TLR9 in a pre-clinical model.
Allen A, Wang C, Caproni LJ, Sugiyarto G, Harden E, Douglas LR, Duriez PJ, Karbowniczek K, Extance J, Rothwell PJ, Orefo I, Tite JP, Stevenson FK, Ottensmeier CH, Savelyeva N.
Allen A, et al. Among authors: karbowniczek k.
Cancer Immunol Immunother. 2018 Apr;67(4):627-638. doi: 10.1007/s00262-017-2111-y. Epub 2018 Jan 12.
Cancer Immunol Immunother. 2018.
PMID: 29330557
Free PMC article.
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CAR T Cell Generation by piggyBac Transposition from Linear Doggybone DNA Vectors Requires Transposon DNA-Flanking Regions.
Bishop DC, Caproni L, Gowrishankar K, Legiewicz M, Karbowniczek K, Tite J, Gottlieb DJ, Micklethwaite KP.
Bishop DC, et al. Among authors: karbowniczek k.
Mol Ther Methods Clin Dev. 2020 Jan 16;17:359-368. doi: 10.1016/j.omtm.2019.12.020. eCollection 2020 Jun 12.
Mol Ther Methods Clin Dev. 2020.
PMID: 32071928
Free PMC article.
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Safe and stable generation of induced pluripotent stem cells using doggybone DNA vectors.
Thornton CD, Fielding S, Karbowniczek K, Roig-Merino A, Burrows AE, FitzPatrick LM, Sharaireh A, Tite JP, Mole SE, Harbottle RP, Caproni LJ, McKay TR.
Thornton CD, et al. Among authors: karbowniczek k.
Mol Ther Methods Clin Dev. 2021 Oct 5;23:348-358. doi: 10.1016/j.omtm.2021.09.018. eCollection 2021 Dec 10.
Mol Ther Methods Clin Dev. 2021.
PMID: 34729381
Free PMC article.
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