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Discovery and optimization of a broadly-neutralizing human monoclonal antibody against long-chain α-neurotoxins from snakes.
Ledsgaard L, Wade J, Jenkins TP, Boddum K, Oganesyan I, Harrison JA, Villar P, Leah RA, Zenobi R, Schoffelen S, Voldborg B, Ljungars A, McCafferty J, Lomonte B, Gutiérrez JM, Laustsen AH, Karatt-Vellatt A. Ledsgaard L, et al. Among authors: karatt vellatt a. Nat Commun. 2023 Feb 8;14(1):682. doi: 10.1038/s41467-023-36393-4. Nat Commun. 2023. PMID: 36755049 Free PMC article.
Basics of Antibody Phage Display Technology.
Ledsgaard L, Kilstrup M, Karatt-Vellatt A, McCafferty J, Laustsen AH. Ledsgaard L, et al. Among authors: karatt vellatt a. Toxins (Basel). 2018 Jun 9;10(6):236. doi: 10.3390/toxins10060236. Toxins (Basel). 2018. PMID: 29890762 Free PMC article. Review.
In vivo neutralization of dendrotoxin-mediated neurotoxicity of black mamba venom by oligoclonal human IgG antibodies.
Laustsen AH, Karatt-Vellatt A, Masters EW, Arias AS, Pus U, Knudsen C, Oscoz S, Slavny P, Griffiths DT, Luther AM, Leah RA, Lindholm M, Lomonte B, Gutiérrez JM, McCafferty J. Laustsen AH, et al. Among authors: karatt vellatt a. Nat Commun. 2018 Oct 2;9(1):3928. doi: 10.1038/s41467-018-06086-4. Nat Commun. 2018. PMID: 30279409 Free PMC article.
Publisher Correction: In vivo neutralization of dendrotoxin-mediated neurotoxicity of black mamba venom by oligoclonal human IgG antibodies.
Laustsen AH, Karatt-Vellatt A, Masters EW, Arias AS, Pus U, Knudsen C, Oscoz S, Slavny P, Griffiths DT, Luther AM, Leah RA, Lindholm M, Lomonte B, Gutiérrez JM, McCafferty J. Laustsen AH, et al. Among authors: karatt vellatt a. Nat Commun. 2018 Nov 20;9(1):4957. doi: 10.1038/s41467-018-07480-8. Nat Commun. 2018. PMID: 30459411 Free PMC article.
Cross-Reactive SARS-CoV-2 Neutralizing Antibodies From Deep Mining of Early Patient Responses.
Bullen G, Galson JD, Hall G, Villar P, Moreels L, Ledsgaard L, Mattiuzzo G, Bentley EM, Masters EW, Tang D, Millett S, Tongue D, Brown R, Diamantopoulos I, Parthiban K, Tebbutt C, Leah R, Chaitanya K, Ergueta-Carballo S, Pazeraitis D, Surade SB, Ashiru O, Crippa L, Cowan R, Bowler MW, Campbell JI, Lee WJ, Carr MD, Matthews D, Pfeffer P, Hufton SE, Sawmynaden K, Osbourn J, McCafferty J, Karatt-Vellatt A. Bullen G, et al. Among authors: karatt vellatt a. Front Immunol. 2021 Jun 15;12:678570. doi: 10.3389/fimmu.2021.678570. eCollection 2021. Front Immunol. 2021. PMID: 34211469 Free PMC article.
In vitro discovery of a human monoclonal antibody that neutralizes lethality of cobra snake venom.
Ledsgaard L, Laustsen AH, Pus U, Wade J, Villar P, Boddum K, Slavny P, Masters EW, Arias AS, Oscoz S, Griffiths DT, Luther AM, Lindholm M, Leah RA, Møller MS, Ali H, McCafferty J, Lomonte B, Gutiérrez JM, Karatt-Vellatt A. Ledsgaard L, et al. Among authors: karatt vellatt a. MAbs. 2022 Jan-Dec;14(1):2085536. doi: 10.1080/19420862.2022.2085536. MAbs. 2022. PMID: 35699567 Free PMC article.
Antibody-dependent enhancement of toxicity of myotoxin II from Bothrops asper.
Sørensen CV, Fernández J, Adams AC, Wildenauer HHK, Schoffelen S, Ledsgaard L, Pucca MB, Fiebig M, Cerni FA, Tulika T, Voldborg BG, Karatt-Vellatt A, Morth JP, Ljungars A, Grav LM, Lomonte B, Laustsen AH. Sørensen CV, et al. Among authors: karatt vellatt a. Nat Commun. 2024 Jan 16;15(1):173. doi: 10.1038/s41467-023-42624-5. Nat Commun. 2024. PMID: 38228619 Free PMC article.
14 results