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Nutrient scavenging-fueled growth in pancreatic cancer depends on caveolae-mediated endocytosis under nutrient-deprived conditions.
Wolfe AR, Cui T, Baie S, Corrales-Guerrero S, Webb A, Castro-Aceituno V, Shyu DL, Karasinska JM, Topham JT, Renouf DJ, Schaeffer DF, Halloran M, Packard R, Robb R, Chen W, Denko N, Lisanti M, Thompson TC, Frank P, Williams TM. Wolfe AR, et al. Among authors: karasinska jm. Sci Adv. 2024 Mar;10(9):eadj3551. doi: 10.1126/sciadv.adj3551. Epub 2024 Mar 1. Sci Adv. 2024. PMID: 38427741 Free PMC article.
Altered Gene Expression along the Glycolysis-Cholesterol Synthesis Axis Is Associated with Outcome in Pancreatic Cancer.
Karasinska JM, Topham JT, Kalloger SE, Jang GH, Denroche RE, Culibrk L, Williamson LM, Wong HL, Lee MKC, O'Kane GM, Moore RA, Mungall AJ, Moore MJ, Warren C, Metcalfe A, Notta F, Knox JJ, Gallinger S, Laskin J, Marra MA, Jones SJM, Renouf DJ, Schaeffer DF. Karasinska JM, et al. Clin Cancer Res. 2020 Jan 1;26(1):135-146. doi: 10.1158/1078-0432.CCR-19-1543. Epub 2019 Sep 3. Clin Cancer Res. 2020. PMID: 31481506
Tumor infiltrating neutrophils and gland formation predict overall survival and molecular subgroups in pancreatic ductal adenocarcinoma.
Naso JR, Topham JT, Karasinska JM, Lee MKC, Kalloger SE, Wong HL, Nelson J, Moore RA, Mungall AJ, Jones SJM, Laskin J, Marra MA, Renouf DJ, Schaeffer DF. Naso JR, et al. Among authors: karasinska jm. Cancer Med. 2021 Feb;10(3):1155-1165. doi: 10.1002/cam4.3695. Epub 2020 Dec 28. Cancer Med. 2021. PMID: 33372414 Free PMC article.
Subtype-Discordant Pancreatic Ductal Adenocarcinoma Tumors Show Intermediate Clinical and Molecular Characteristics.
Topham JT, Karasinska JM, Lee MKC, Csizmok V, Williamson LM, Jang GH, Denroche RE, Tsang ES, Kalloger SE, Wong HL, O'Kane GM, Moore RA, Mungall AJ, Notta F, Loree JM, Wilson JM, Bathe O, Tang PA, Goodwin R, Knox JJ, Gallinger S, Laskin J, Marra MA, Jones SJM, Renouf DJ, Schaeffer DF. Topham JT, et al. Among authors: karasinska jm. Clin Cancer Res. 2021 Jan 1;27(1):150-157. doi: 10.1158/1078-0432.CCR-20-2831. Epub 2020 Oct 13. Clin Cancer Res. 2021. PMID: 33051307
Clinically impactful metabolic subtypes of pancreatic ductal adenocarcinoma (PDAC).
Pervin J, Asad M, Cao S, Jang GH, Feizi N, Haibe-Kains B, Karasinska JM, O'Kane GM, Gallinger S, Schaeffer DF, Renouf DJ, Zogopoulos G, Bathe OF. Pervin J, et al. Among authors: karasinska jm. Front Genet. 2023 Oct 30;14:1282824. doi: 10.3389/fgene.2023.1282824. eCollection 2023. Front Genet. 2023. PMID: 38028629 Free PMC article.
Regulation of pH by Carbonic Anhydrase 9 Mediates Survival of Pancreatic Cancer Cells With Activated KRAS in Response to Hypoxia.
McDonald PC, Chafe SC, Brown WS, Saberi S, Swayampakula M, Venkateswaran G, Nemirovsky O, Gillespie JA, Karasinska JM, Kalloger SE, Supuran CT, Schaeffer DF, Bashashati A, Shah SP, Topham JT, Yapp DT, Li J, Renouf DJ, Stanger BZ, Dedhar S. McDonald PC, et al. Among authors: karasinska jm. Gastroenterology. 2019 Sep;157(3):823-837. doi: 10.1053/j.gastro.2019.05.004. Epub 2019 May 9. Gastroenterology. 2019. PMID: 31078621 Free article.
Endogenous Retrovirus Transcript Levels Are Associated with Immunogenic Signatures in Multiple Metastatic Cancer Types.
Topham JT, Titmuss E, Pleasance ED, Williamson LM, Karasinska JM, Culibrk L, Lee MKC, Mendis S, Denroche RE, Jang GH, Kalloger SE, Wong HL, Moore RA, Mungall AJ, O'Kane GM, Knox JJ, Gallinger S, Loree JM, Mager DL, Laskin J, Marra MA, Jones SJM, Schaeffer DF, Renouf DJ. Topham JT, et al. Among authors: karasinska jm. Mol Cancer Ther. 2020 Sep;19(9):1889-1897. doi: 10.1158/1535-7163.MCT-20-0094. Epub 2020 Jun 9. Mol Cancer Ther. 2020. PMID: 32518206
Delving into Early-onset Pancreatic Ductal Adenocarcinoma: How Does Age Fit In?
Tsang ES, Topham JT, Karasinska JM, Lee MKC, Williamson LM, Mendis S, Denroche RE, Jang GH, Kalloger SE, Moore RA, Mungall AJ, Bathe OF, Tang PA, Notta F, Wilson JM, Laskin J, O'Kane GM, Knox JJ, Goodwin RA, Loree JM, Jones SJM, Marra MA, Gallinger S, Schaeffer DF, Renouf DJ. Tsang ES, et al. Among authors: karasinska jm. Clin Cancer Res. 2021 Jan 1;27(1):246-254. doi: 10.1158/1078-0432.CCR-20-1042. Epub 2020 Sep 21. Clin Cancer Res. 2021. PMID: 32958704
43 results