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Highly immunogenic cancer cells require activation of the WNT pathway for immunological escape.
Takeuchi Y, Tanegashima T, Sato E, Irie T, Sai A, Itahashi K, Kumagai S, Tada Y, Togashi Y, Koyama S, Akbay EA, Karasaki T, Kataoka K, Funaki S, Shintani Y, Nagatomo I, Kida H, Ishii G, Miyoshi T, Aokage K, Kakimi K, Ogawa S, Okumura M, Eto M, Kumanogoh A, Tsuboi M, Nishikawa H. Takeuchi Y, et al. Among authors: karasaki t. Sci Immunol. 2021 Nov 12;6(65):eabc6424. doi: 10.1126/sciimmunol.abc6424. Epub 2021 Nov 12. Sci Immunol. 2021. PMID: 34767457
Advances in personalized cancer immunotherapy.
Kakimi K, Karasaki T, Matsushita H, Sugie T. Kakimi K, et al. Among authors: karasaki t. Breast Cancer. 2017 Jan;24(1):16-24. doi: 10.1007/s12282-016-0688-1. Epub 2016 Mar 21. Breast Cancer. 2017. PMID: 27000871 Review.
[Neoantigens and Whole-Exome Sequencing].
Karasaki T, Nakajima J, Kakimi K. Karasaki T, et al. Gan To Kagaku Ryoho. 2016 Jul;43(7):791-7. Gan To Kagaku Ryoho. 2016. PMID: 27431622 Review. Japanese.
The frequency of neoantigens per somatic mutation rather than overall mutational load or number of predicted neoantigens per se is a prognostic factor in ovarian clear cell carcinoma.
Matsushita H, Hasegawa K, Oda K, Yamamoto S, Nishijima A, Imai Y, Asada K, Ikeda Y, Karasaki T, Fujiwara K, Aburatani H, Kakimi K. Matsushita H, et al. Among authors: karasaki t. Oncoimmunology. 2017 Jun 16;6(8):e1338996. doi: 10.1080/2162402X.2017.1338996. eCollection 2017. Oncoimmunology. 2017. PMID: 28920005 Free PMC article.
NK cell and IFN signatures are positive prognostic biomarkers for resectable pancreatic cancer.
Hoshikawa M, Aoki T, Matsushita H, Karasaki T, Hosoi A, Odaira K, Fujieda N, Kobayashi Y, Kambara K, Ohara O, Arita J, Hasegawa K, Kakimi K, Kokudo N. Hoshikawa M, et al. Among authors: karasaki t. Biochem Biophys Res Commun. 2018 Jan 8;495(2):2058-2065. doi: 10.1016/j.bbrc.2017.12.083. Epub 2017 Dec 15. Biochem Biophys Res Commun. 2018. PMID: 29253566
Reduced Neoantigen Expression Revealed by Longitudinal Multiomics as a Possible Immune Evasion Mechanism in Glioma.
Nejo T, Matsushita H, Karasaki T, Nomura M, Saito K, Tanaka S, Takayanagi S, Hana T, Takahashi S, Kitagawa Y, Koike T, Kobayashi Y, Nagae G, Yamamoto S, Ueda H, Tatsuno K, Narita Y, Nagane M, Ueki K, Nishikawa R, Aburatani H, Mukasa A, Saito N, Kakimi K. Nejo T, et al. Among authors: karasaki t. Cancer Immunol Res. 2019 Jul;7(7):1148-1161. doi: 10.1158/2326-6066.CIR-18-0599. Epub 2019 May 14. Cancer Immunol Res. 2019. PMID: 31088845
71 results