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210 results

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Reduced endoglin activity limits cardiac fibrosis and improves survival in heart failure.
Kapur NK, Wilson S, Yunis AA, Qiao X, Mackey E, Paruchuri V, Baker C, Aronovitz MJ, Karumanchi SA, Letarte M, Kass DA, Mendelsohn ME, Karas RH. Kapur NK, et al. Among authors: karas rh. Circulation. 2012 Jun 5;125(22):2728-38. doi: 10.1161/CIRCULATIONAHA.111.080002. Epub 2012 May 16. Circulation. 2012. PMID: 22592898 Free PMC article.
Mutation of the protein kinase I alpha leucine zipper domain produces hypertension and progressive left ventricular hypertrophy: a novel mouse model of age-dependent hypertensive heart disease.
Blanton RM, Takimoto E, Aronovitz M, Thoonen R, Kass DA, Karas RH, Mendelsohn ME. Blanton RM, et al. Among authors: karas rh. J Gerontol A Biol Sci Med Sci. 2013 Nov;68(11):1351-5. doi: 10.1093/gerona/glt042. Epub 2013 May 8. J Gerontol A Biol Sci Med Sci. 2013. PMID: 23657971 Free PMC article.
Left Ventricular T-Cell Recruitment Contributes to the Pathogenesis of Heart Failure.
Nevers T, Salvador AM, Grodecki-Pena A, Knapp A, Velázquez F, Aronovitz M, Kapur NK, Karas RH, Blanton RM, Alcaide P. Nevers T, et al. Among authors: karas rh. Circ Heart Fail. 2015 Jul;8(4):776-87. doi: 10.1161/CIRCHEARTFAILURE.115.002225. Epub 2015 May 28. Circ Heart Fail. 2015. PMID: 26022677 Free PMC article.
Mixed lineage kinase-3 prevents cardiac dysfunction and structural remodeling with pressure overload.
Calamaras TD, Baumgartner RA, Aronovitz MJ, McLaughlin AL, Tam K, Richards DA, Cooper CW, Li N, Baur WE, Qiao X, Wang GR, Davis RJ, Kapur NK, Karas RH, Blanton RM. Calamaras TD, et al. Among authors: karas rh. Am J Physiol Heart Circ Physiol. 2019 Jan 1;316(1):H145-H159. doi: 10.1152/ajpheart.00029.2018. Epub 2018 Oct 26. Am J Physiol Heart Circ Physiol. 2019. PMID: 30362822 Free PMC article.
MLK3 mediates impact of PKG1α on cardiac function and controls blood pressure through separate mechanisms.
Calamaras TD, Pande S, Baumgartner RA, Kim SK, McCarthy JC, Martin GL, Tam K, McLaughlin AL, Wang GR, Aronovitz MJ, Lin W, Aguirre JI, Baca P, Liu P, Richards DA, Davis RJ, Karas RH, Jaffe IZ, Blanton RM. Calamaras TD, et al. Among authors: karas rh. JCI Insight. 2021 Sep 22;6(18):e149075. doi: 10.1172/jci.insight.149075. JCI Insight. 2021. PMID: 34324442 Free PMC article.
The mitochondrial regulator PGC1α is induced by cGMP-PKG signaling and mediates the protective effects of phosphodiesterase 5 inhibition in heart failure.
Zhu G, Ueda K, Hashimoto M, Zhang M, Sasaki M, Kariya T, Sasaki H, Kaludercic N, Lee DI, Bedja D, Gabrielson M, Yuan Y, Paolocci N, Blanton RM, Karas RH, Mendelsohn ME, O'Rourke B, Kass DA, Takimoto E. Zhu G, et al. Among authors: karas rh. FEBS Lett. 2022 Jan;596(1):17-28. doi: 10.1002/1873-3468.14228. Epub 2021 Nov 19. FEBS Lett. 2022. PMID: 34778969 Free PMC article.
210 results