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Anilinoquinazoline inhibitors of fructose 1,6-bisphosphatase bind at a novel allosteric site: synthesis, in vitro characterization, and X-ray crystallography.
Wright SW, Carlo AA, Carty MD, Danley DE, Hageman DL, Karam GA, Levy CB, Mansour MN, Mathiowetz AM, McClure LD, Nestor NB, McPherson RK, Pandit J, Pustilnik LR, Schulte GK, Soeller WC, Treadway JL, Wang IK, Bauer PH. Wright SW, et al. Among authors: karam ga. J Med Chem. 2002 Aug 29;45(18):3865-77. doi: 10.1021/jm010496a. J Med Chem. 2002. PMID: 12190310
Crystal structure of cholesteryl ester transfer protein reveals a long tunnel and four bound lipid molecules.
Qiu X, Mistry A, Ammirati MJ, Chrunyk BA, Clark RW, Cong Y, Culp JS, Danley DE, Freeman TB, Geoghegan KF, Griffor MC, Hawrylik SJ, Hayward CM, Hensley P, Hoth LR, Karam GA, Lira ME, Lloyd DB, McGrath KM, Stutzman-Engwall KJ, Subashi AK, Subashi TA, Thompson JF, Wang IK, Zhao H, Seddon AP. Qiu X, et al. Among authors: karam ga. Nat Struct Mol Biol. 2007 Feb;14(2):106-13. doi: 10.1038/nsmb1197. Epub 2007 Jan 21. Nat Struct Mol Biol. 2007. PMID: 17237796
Biochemical and pharmacological characterization of human c-Met neutralizing monoclonal antibody CE-355621.
Michaud NR, Jani JP, Hillerman S, Tsaparikos KE, Barbacci-Tobin EG, Knauth E, Putz H Jr, Campbell M, Karam GA, Chrunyk B, Gebhard DF, Green LL, Xu JJ, Dunn MC, Coskran TM, Lapointe JM, Cohen BD, Coleman KG, Bedian V, Vincent P, Kajiji S, Steyn SJ, Borzillo GV, Los G. Michaud NR, et al. Among authors: karam ga. MAbs. 2012 Nov-Dec;4(6):710-23. doi: 10.4161/mabs.22160. Epub 2012 Sep 24. MAbs. 2012. PMID: 23007574 Free PMC article.
Development of an Educational Video for Self-Assessment of Patients with RA: Steps, Challenges, and Responses.
Ziade N, Arayssi T, Elzorkany B, Daher A, Karam GA, Jbara MA, Aiko A, Alam E, Emadi SA, Mashaleh MA, Badsha H, Kibbi LE, Halabi H, Harifi G, Khan B, Masri AF, Menassa J, Merashli M, Merheb G, Messaykeh J, Mroue' K, Saad S, Salloum N, Uthman I, Masri B. Ziade N, et al. Among authors: karam ga. Mediterr J Rheumatol. 2021 Mar 4;32(1):66-73. doi: 10.31138/mjr.32.1.66. eCollection 2021 Mar. Mediterr J Rheumatol. 2021. PMID: 34386703 Free PMC article.
20 results