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Patient-derived melanoma organoid models facilitate the assessment of immunotherapies.
Ou L, Liu S, Wang H, Guo Y, Guan L, Shen L, Luo R, Elder DE, Huang AC, Karakousis G, Miura J, Mitchell T, Schuchter L, Amaravadi R, Flowers A, Mou H, Yi F, Guo W, Ko J, Chen Q, Tian B, Herlyn M, Xu X. Ou L, et al. Among authors: karakousis g. EBioMedicine. 2023 Jun;92:104614. doi: 10.1016/j.ebiom.2023.104614. Epub 2023 May 23. EBioMedicine. 2023. PMID: 37229906 Free PMC article.
Predictors of regional nodal disease in patients with thin melanomas.
Karakousis GC, Gimotty PA, Botbyl JD, Kesmodel SB, Elder DE, Elenitsas R, Ming ME, Guerry D, Fraker DL, Czerniecki BJ, Spitz FR. Karakousis GC, et al. Ann Surg Oncol. 2006 Apr;13(4):533-41. doi: 10.1245/ASO.2006.05.011. Epub 2006 Mar 7. Ann Surg Oncol. 2006. PMID: 16523360
Lymphatic invasion revealed by multispectral imaging is common in primary melanomas and associates with prognosis.
Xu X, Gimotty PA, Guerry D, Karakousis G, Van Belle P, Liang H, Montone K, Pasha T, Ming ME, Acs G, Feldman M, Barth S, Hammond R, Elenitsas R, Zhang PJ, Elder DE. Xu X, et al. Among authors: karakousis g. Hum Pathol. 2008 Jun;39(6):901-9. doi: 10.1016/j.humpath.2007.10.017. Epub 2008 Apr 28. Hum Pathol. 2008. PMID: 18440591 Free PMC article.
Melanoma adapts to RAF/MEK inhibitors through FOXD3-mediated upregulation of ERBB3.
Abel EV, Basile KJ, Kugel CH 3rd, Witkiewicz AK, Le K, Amaravadi RK, Karakousis GC, Xu X, Xu W, Schuchter LM, Lee JB, Ertel A, Fortina P, Aplin AE. Abel EV, et al. J Clin Invest. 2013 May;123(5):2155-68. doi: 10.1172/JCI65780. Epub 2013 Apr 1. J Clin Invest. 2013. PMID: 23543055 Free PMC article.
Local immune response predicts survival in patients with thick (t4) melanomas.
Cintolo JA, Gimotty P, Blair A, Guerry D, Elder DE, Hammond R, Elenitsas R, Xu X, Fraker D, Schuchter LM, Czerniecki BJ, Karakousis G. Cintolo JA, et al. Among authors: karakousis g. Ann Surg Oncol. 2013 Oct;20(11):3610-7. doi: 10.1245/s10434-013-3086-3. Epub 2013 Jul 10. Ann Surg Oncol. 2013. PMID: 23838911
Concurrent MEK2 mutation and BRAF amplification confer resistance to BRAF and MEK inhibitors in melanoma.
Villanueva J, Infante JR, Krepler C, Reyes-Uribe P, Samanta M, Chen HY, Li B, Swoboda RK, Wilson M, Vultur A, Fukunaba-Kalabis M, Wubbenhorst B, Chen TY, Liu Q, Sproesser K, DeMarini DJ, Gilmer TM, Martin AM, Marmorstein R, Schultz DC, Speicher DW, Karakousis GC, Xu W, Amaravadi RK, Xu X, Schuchter LM, Herlyn M, Nathanson KL. Villanueva J, et al. Cell Rep. 2013 Sep 26;4(6):1090-9. doi: 10.1016/j.celrep.2013.08.023. Epub 2013 Sep 19. Cell Rep. 2013. PMID: 24055054 Free PMC article.
344 results