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Impaired ketogenesis ties metabolism to T cell dysfunction in COVID-19.
Karagiannis F, Peukert K, Surace L, Michla M, Nikolka F, Fox M, Weiss P, Feuerborn C, Maier P, Schulz S, Al B, Seeliger B, Welte T, David S, Grondman I, de Nooijer AH, Pickkers P, Kleiner JL, Berger MM, Brenner T, Putensen C; Bonn COVIMMUNE Consortium; Kato H, Garbi N, Netea MG, Hiller K, Placek K, Bode C, Wilhelm C. Karagiannis F, et al. Nature. 2022 Sep;609(7928):801-807. doi: 10.1038/s41586-022-05128-8. Epub 2022 Jul 28. Nature. 2022. PMID: 35901960 Free PMC article.
Properties of myelin altered peptide ligand cyclo(87-99)(Ala91,Ala96)MBP87-99 render it a promising drug lead for immunotherapy of multiple sclerosis.
Deraos G, Rodi M, Kalbacher H, Chatzantoni K, Karagiannis F, Synodinos L, Plotas P, Papalois A, Dimisianos N, Papathanasopoulos P, Gatos D, Tselios T, Apostolopoulos V, Mouzaki A, Matsoukas J. Deraos G, et al. Among authors: karagiannis f. Eur J Med Chem. 2015 Aug 28;101:13-23. doi: 10.1016/j.ejmech.2015.06.015. Epub 2015 Jun 17. Eur J Med Chem. 2015. PMID: 26112377
Ets-2 Acts As a Transcriptional Repressor of the Human Immunodeficiency Virus Type 1 through Binding to a Repressor-Activator Target Sequence of 5'-LTR.
Panagoulias I, Karagiannis F, Aggeletopoulou I, Georgakopoulos T, Argyropoulos CP, Akinosoglou K, Gogos C, Skoutelis A, Mouzaki A. Panagoulias I, et al. Among authors: karagiannis f. Front Immunol. 2018 Jan 4;8:1924. doi: 10.3389/fimmu.2017.01924. eCollection 2017. Front Immunol. 2018. PMID: 29354130 Free PMC article.