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Engineered ACE2 receptor traps potently neutralize SARS-CoV-2.
Glasgow A, Glasgow J, Limonta D, Solomon P, Lui I, Zhang Y, Nix MA, Rettko NJ, Zha S, Yamin R, Kao K, Rosenberg OS, Ravetch JV, Wiita AP, Leung KK, Lim SA, Zhou XX, Hobman TC, Kortemme T, Wells JA. Glasgow A, et al. Among authors: kao k. Proc Natl Acad Sci U S A. 2020 Nov 10;117(45):28046-28055. doi: 10.1073/pnas.2016093117. Epub 2020 Oct 22. Proc Natl Acad Sci U S A. 2020. PMID: 33093202 Free PMC article.
Engineered ACE2 receptor traps potently neutralize SARS-CoV-2.
Glasgow A, Glasgow J, Limonta D, Solomon P, Lui I, Zhang Y, Nix MA, Rettko NJ, Lim SA, Zha S, Yamin R, Kao K, Rosenberg OS, Ravetch JV, Wiita AP, Leung KK, Zhou XX, Hobman TC, Kortemme T, Wells JA. Glasgow A, et al. Among authors: kao k. bioRxiv [Preprint]. 2020 Aug 4:2020.07.31.231746. doi: 10.1101/2020.07.31.231746. bioRxiv. 2020. PMID: 32766586 Free PMC article. Updated. Preprint.
Fc-engineered antibody therapeutics with improved anti-SARS-CoV-2 efficacy.
Yamin R, Jones AT, Hoffmann HH, Schäfer A, Kao KS, Francis RL, Sheahan TP, Baric RS, Rice CM, Ravetch JV, Bournazos S. Yamin R, et al. Nature. 2021 Nov;599(7885):465-470. doi: 10.1038/s41586-021-04017-w. Epub 2021 Sep 21. Nature. 2021. PMID: 34547765 Free PMC article.
Combining CD47 blockade with trastuzumab eliminates HER2-positive breast cancer cells and overcomes trastuzumab tolerance.
Upton R, Banuelos A, Feng D, Biswas T, Kao K, McKenna K, Willingham S, Ho PY, Rosental B, Tal MC, Raveh T, Volkmer JP, Pegram MD, Weissman IL. Upton R, et al. Among authors: kao k. Proc Natl Acad Sci U S A. 2021 Jul 20;118(29):e2026849118. doi: 10.1073/pnas.2026849118. Proc Natl Acad Sci U S A. 2021. PMID: 34257155 Free PMC article.
Structural titration of receptor ion channel GLIC gating by HS-AFM.
Ruan Y, Kao K, Lefebvre S, Marchesi A, Corringer PJ, Hite RK, Scheuring S. Ruan Y, et al. Among authors: kao k. Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):10333-10338. doi: 10.1073/pnas.1805621115. Epub 2018 Sep 4. Proc Natl Acad Sci U S A. 2018. PMID: 30181288 Free PMC article.
Engagement of MHC class I by the inhibitory receptor LILRB1 suppresses macrophages and is a target of cancer immunotherapy.
Barkal AA, Weiskopf K, Kao KS, Gordon SR, Rosental B, Yiu YY, George BM, Markovic M, Ring NG, Tsai JM, McKenna KM, Ho PY, Cheng RZ, Chen JY, Barkal LJ, Ring AM, Weissman IL, Maute RL. Barkal AA, et al. Among authors: kao ks. Nat Immunol. 2018 Jan;19(1):76-84. doi: 10.1038/s41590-017-0004-z. Epub 2017 Nov 27. Nat Immunol. 2018. PMID: 29180808 Free PMC article.
Normal and Neoplastic Stem Cells.
McCracken MN, George BM, Kao KS, Marjon KD, Raveh T, Weissman IL. McCracken MN, et al. Cold Spring Harb Symp Quant Biol. 2016;81:1-9. doi: 10.1101/sqb.2016.81.030965. Epub 2017 Apr 17. Cold Spring Harb Symp Quant Biol. 2016. PMID: 28416577 Free PMC article. Review.
Programmed cell removal by calreticulin in tissue homeostasis and cancer.
Feng M, Marjon KD, Zhu F, Weissman-Tsukamoto R, Levett A, Sullivan K, Kao KS, Markovic M, Bump PA, Jackson HM, Choi TS, Chen J, Banuelos AM, Liu J, Gip P, Cheng L, Wang D, Weissman IL. Feng M, et al. Among authors: kao ks. Nat Commun. 2018 Aug 10;9(1):3194. doi: 10.1038/s41467-018-05211-7. Nat Commun. 2018. PMID: 30097573 Free PMC article.
811 results