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Generation of host-directed and virus-specific antivirals using targeted protein degradation promoted by small molecules and viral RNA mimics.
Zhao N, Ho JSY, Meng F, Zheng S, Kurland AP, Tian L, Rea-Moreno M, Song X, Seo JS, Kaniskan HÜ, Te Velthuis AJW, Tortorella D, Chen YW, Johnson JR, Jin J, Marazzi I. Zhao N, et al. Among authors: kaniskan hu. Cell Host Microbe. 2023 Jul 12;31(7):1154-1169.e10. doi: 10.1016/j.chom.2023.05.030. Epub 2023 Jun 5. Cell Host Microbe. 2023. PMID: 37339625 Free article.
Selective inhibitors of protein methyltransferases.
Kaniskan HÜ, Konze KD, Jin J. Kaniskan HÜ, et al. J Med Chem. 2015 Feb 26;58(4):1596-629. doi: 10.1021/jm501234a. Epub 2014 Dec 2. J Med Chem. 2015. PMID: 25406853 Free PMC article.
Chemical probes of histone lysine methyltransferases.
Kaniskan HÜ, Jin J. Kaniskan HÜ, et al. ACS Chem Biol. 2015 Jan 16;10(1):40-50. doi: 10.1021/cb500785t. Epub 2014 Nov 25. ACS Chem Biol. 2015. PMID: 25423077 Free PMC article. Review.
Inhibitors of Protein Methyltransferases and Demethylases.
Kaniskan HÜ, Martini ML, Jin J. Kaniskan HÜ, et al. Chem Rev. 2018 Feb 14;118(3):989-1068. doi: 10.1021/acs.chemrev.6b00801. Epub 2017 Mar 24. Chem Rev. 2018. PMID: 28338320 Free PMC article. Review.
Histone Lysine Methylation Dynamics Control EGFR DNA Copy-Number Amplification.
Clarke TL, Tang R, Chakraborty D, Van Rechem C, Ji F, Mishra S, Ma A, Kaniskan HÜ, Jin J, Lawrence MS, Sadreyev RI, Whetstine JR. Clarke TL, et al. Among authors: kaniskan hu. Cancer Discov. 2020 Feb;10(2):306-325. doi: 10.1158/2159-8290.CD-19-0463. Epub 2019 Nov 27. Cancer Discov. 2020. PMID: 31776131 Free PMC article.
54 results