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Pathological α-synuclein transmission initiated by binding lymphocyte-activation gene 3.
Mao X, Ou MT, Karuppagounder SS, Kam TI, Yin X, Xiong Y, Ge P, Umanah GE, Brahmachari S, Shin JH, Kang HC, Zhang J, Xu J, Chen R, Park H, Andrabi SA, Kang SU, Gonçalves RA, Liang Y, Zhang S, Qi C, Lam S, Keiler JA, Tyson J, Kim D, Panicker N, Yun SP, Workman CJ, Vignali DA, Dawson VL, Ko HS, Dawson TM. Mao X, et al. Among authors: kang hc, kang su. Science. 2016 Sep 30;353(6307):aah3374. doi: 10.1126/science.aah3374. Science. 2016. PMID: 27708076 Free PMC article.
Parthanatos mediates AIMP2-activated age-dependent dopaminergic neuronal loss.
Lee Y, Karuppagounder SS, Shin JH, Lee YI, Ko HS, Swing D, Jiang H, Kang SU, Lee BD, Kang HC, Kim D, Tessarollo L, Dawson VL, Dawson TM. Lee Y, et al. Among authors: kang hc, kang su. Nat Neurosci. 2013 Oct;16(10):1392-400. doi: 10.1038/nn.3500. Epub 2013 Aug 25. Nat Neurosci. 2013. PMID: 23974709 Free PMC article.
Parkin loss leads to PARIS-dependent declines in mitochondrial mass and respiration.
Stevens DA, Lee Y, Kang HC, Lee BD, Lee YI, Bower A, Jiang H, Kang SU, Andrabi SA, Dawson VL, Shin JH, Dawson TM. Stevens DA, et al. Among authors: kang hc, kang su. Proc Natl Acad Sci U S A. 2015 Sep 15;112(37):11696-701. doi: 10.1073/pnas.1500624112. Epub 2015 Aug 31. Proc Natl Acad Sci U S A. 2015. PMID: 26324925 Free PMC article.
Adult Conditional Knockout of PGC-1α Leads to Loss of Dopamine Neurons.
Jiang H, Kang SU, Zhang S, Karuppagounder S, Xu J, Lee YK, Kang BG, Lee Y, Zhang J, Pletnikova O, Troncoso JC, Pirooznia S, Andrabi SA, Dawson VL, Dawson TM. Jiang H, et al. Among authors: kang bg, kang su. eNeuro. 2016 Sep 2;3(4):ENEURO.0183-16.2016. doi: 10.1523/ENEURO.0183-16.2016. eCollection 2016 Jul-Aug. eNeuro. 2016. PMID: 27622213 Free PMC article.
High-Content Genome-Wide RNAi Screen Reveals CCR3 as a Key Mediator of Neuronal Cell Death.
Zhang J, Wang H, Sherbini O, Ling-Lin Pai E, Kang SU, Kwon JS, Yang J, He W, Wang H, Eacker SM, Chi Z, Mao X, Xu J, Jiang H, Andrabi SA, Dawson TM, Dawson VL. Zhang J, et al. Among authors: kang su. eNeuro. 2016 Oct 24;3(5):ENEURO.0185-16.2016. doi: 10.1523/ENEURO.0185-16.2016. eCollection 2016 Sep-Oct. eNeuro. 2016. PMID: 27822494 Free PMC article.
PINK1 Primes Parkin-Mediated Ubiquitination of PARIS in Dopaminergic Neuronal Survival.
Lee Y, Stevens DA, Kang SU, Jiang H, Lee YI, Ko HS, Scarffe LA, Umanah GE, Kang H, Ham S, Kam TI, Allen K, Brahmachari S, Kim JW, Neifert S, Yun SP, Fiesel FC, Springer W, Dawson VL, Shin JH, Dawson TM. Lee Y, et al. Among authors: kang h, kang su. Cell Rep. 2017 Jan 24;18(4):918-932. doi: 10.1016/j.celrep.2016.12.090. Cell Rep. 2017. PMID: 28122242 Free PMC article.
Robust kinase- and age-dependent dopaminergic and norepinephrine neurodegeneration in LRRK2 G2019S transgenic mice.
Xiong Y, Neifert S, Karuppagounder SS, Liu Q, Stankowski JN, Lee BD, Ko HS, Lee Y, Grima JC, Mao X, Jiang H, Kang SU, Swing DA, Iacovitti L, Tessarollo L, Dawson TM, Dawson VL. Xiong Y, et al. Among authors: kang su. Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):1635-1640. doi: 10.1073/pnas.1712648115. Epub 2018 Jan 31. Proc Natl Acad Sci U S A. 2018. PMID: 29386392 Free PMC article.
Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson's disease.
Yun SP, Kam TI, Panicker N, Kim S, Oh Y, Park JS, Kwon SH, Park YJ, Karuppagounder SS, Park H, Kim S, Oh N, Kim NA, Lee S, Brahmachari S, Mao X, Lee JH, Kumar M, An D, Kang SU, Lee Y, Lee KC, Na DH, Kim D, Lee SH, Roschke VV, Liddelow SA, Mari Z, Barres BA, Dawson VL, Lee S, Dawson TM, Ko HS. Yun SP, et al. Among authors: kang su. Nat Med. 2018 Jul;24(7):931-938. doi: 10.1038/s41591-018-0051-5. Epub 2018 Jun 11. Nat Med. 2018. PMID: 29892066 Free PMC article.
305 results