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Oncostatin M expression induced by bacterial triggers drives airway inflammatory and mucus secretion in severe asthma.
Headland SE, Dengler HS, Xu D, Teng G, Everett C, Ratsimandresy RA, Yan D, Kang J, Ganeshan K, Nazarova EV, Gierke S, Wedeles CJ, Guidi R, DePianto DJ, Morshead KB, Huynh A, Mills J, Flanagan S, Hambro S, Nunez V, Klementowicz JE, Shi Y, Wang J, Bevers J 3rd, Ramirez-Carrozzi V, Pappu R, Abbas A, Vander Heiden J, Choy DF, Yadav R, Modrusan Z, Panettieri RA Jr, Koziol-White C, Jester WF Jr, Jenkins BJ, Cao Y, Clarke C, Austin C, Lafkas D, Xu M, Wolters PJ, Arron JR, West NR, Wilson MS. Headland SE, et al. Among authors: kang j. Sci Transl Med. 2022 Jan 12;14(627):eabf8188. doi: 10.1126/scitranslmed.abf8188. Epub 2022 Jan 12. Sci Transl Med. 2022. PMID: 35020406
Combined blockade of the IL-13 and IL-33 pathways leads to a greater inhibition of type 2 inflammation over inhibition of either pathway alone.
Ramirez-Carrozzi V, Sambandam A, Zhou M, Yan D, Kang J, Wu X, Suto E, Baca M, Austin C, Xu M, Lee W, Pappu R. Ramirez-Carrozzi V, et al. Among authors: kang j. J Allergy Clin Immunol. 2017 Feb;139(2):705-708.e6. doi: 10.1016/j.jaci.2016.08.026. Epub 2016 Sep 30. J Allergy Clin Immunol. 2017. PMID: 27697499 No abstract available.
Host-derived fatty acids activate type VII secretion in Staphylococcus aureus.
Lopez MS, Tan IS, Yan D, Kang J, McCreary M, Modrusan Z, Austin CD, Xu M, Brown EJ. Lopez MS, et al. Among authors: kang j. Proc Natl Acad Sci U S A. 2017 Oct 17;114(42):11223-11228. doi: 10.1073/pnas.1700627114. Epub 2017 Oct 2. Proc Natl Acad Sci U S A. 2017. PMID: 28973946 Free PMC article.
A Putative Bacterial ABC Transporter Circumvents the Essentiality of Signal Peptidase.
Morisaki JH, Smith PA, Date SV, Kajihara KK, Truong CL, Modrusan Z, Yan D, Kang J, Xu M, Shah IM, Mintzer R, Kofoed EM, Cheung TK, Arnott D, Koehler MF, Heise CE, Brown EJ, Tan MW, Hazenbos WL. Morisaki JH, et al. Among authors: kang j. mBio. 2016 Sep 6;7(5):e00412-16. doi: 10.1128/mBio.00412-16. mBio. 2016. PMID: 27601569 Free PMC article.
Unstable Mechanisms of Resistance to Inhibitors of Escherichia coli Lipoprotein Signal Peptidase.
Pantua H, Skippington E, Braun MG, Noland CL, Diao J, Peng Y, Gloor SL, Yan D, Kang J, Katakam AK, Reeder J, Castanedo GM, Garland K, Komuves L, Sagolla M, Austin CD, Murray J, Xu Y, Modrusan Z, Xu M, Hanan EJ, Kapadia SB. Pantua H, et al. Among authors: kang j. mBio. 2020 Sep 8;11(5):e02018-20. doi: 10.1128/mBio.02018-20. mBio. 2020. PMID: 32900806 Free PMC article.
Peptidoglycan Association of Murein Lipoprotein Is Required for KpsD-Dependent Group 2 Capsular Polysaccharide Expression and Serum Resistance in a Uropathogenic Escherichia coli Isolate.
Diao J, Bouwman C, Yan D, Kang J, Katakam AK, Liu P, Pantua H, Abbas AR, Nickerson NN, Austin C, Reichelt M, Sandoval W, Xu M, Whitfield C, Kapadia SB. Diao J, et al. Among authors: kang j. mBio. 2017 May 23;8(3):e00603-17. doi: 10.1128/mBio.00603-17. mBio. 2017. PMID: 28536290 Free PMC article.
NINJ1 mediates plasma membrane rupture during lytic cell death.
Kayagaki N, Kornfeld OS, Lee BL, Stowe IB, O'Rourke K, Li Q, Sandoval W, Yan D, Kang J, Xu M, Zhang J, Lee WP, McKenzie BS, Ulas G, Payandeh J, Roose-Girma M, Modrusan Z, Reja R, Sagolla M, Webster JD, Cho V, Andrews TD, Morris LX, Miosge LA, Goodnow CC, Bertram EM, Dixit VM. Kayagaki N, et al. Among authors: kang j. Nature. 2021 Mar;591(7848):131-136. doi: 10.1038/s41586-021-03218-7. Epub 2021 Jan 20. Nature. 2021. PMID: 33472215
Inhibition of Escherichia coli Lipoprotein Diacylglyceryl Transferase Is Insensitive to Resistance Caused by Deletion of Braun's Lipoprotein.
Diao J, Komura R, Sano T, Pantua H, Storek KM, Inaba H, Ogawa H, Noland CL, Peng Y, Gloor SL, Yan D, Kang J, Katakam AK, Volny M, Liu P, Nickerson NN, Sandoval W, Austin CD, Murray J, Rutherford ST, Reichelt M, Xu Y, Xu M, Yanagida H, Nishikawa J, Reid PC, Cunningham CN, Kapadia SB. Diao J, et al. Among authors: kang j. J Bacteriol. 2021 Jun 8;203(13):e0014921. doi: 10.1128/JB.00149-21. Epub 2021 Jun 8. J Bacteriol. 2021. PMID: 33875545 Free PMC article.
Deletion of a previously uncharacterized lipoprotein lirL confers resistance to an inhibitor of type II signal peptidase in Acinetobacter baumannii.
Huang KJ, Pantua H, Diao J, Skippington E, Volny M, Sandoval W, Tiku V, Peng Y, Sagolla M, Yan D, Kang J, Katakam AK, Michaelian N, Reichelt M, Tan MW, Austin CD, Xu M, Hanan E, Kapadia SB. Huang KJ, et al. Among authors: kang j. Proc Natl Acad Sci U S A. 2022 Sep 20;119(38):e2123117119. doi: 10.1073/pnas.2123117119. Epub 2022 Sep 13. Proc Natl Acad Sci U S A. 2022. PMID: 36099298 Free PMC article.
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