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Inhibition of Pyruvate Dehydrogenase Kinase 2 Protects Against Hepatic Steatosis Through Modulation of Tricarboxylic Acid Cycle Anaplerosis and Ketogenesis.
Go Y, Jeong JY, Jeoung NH, Jeon JH, Park BY, Kang HJ, Ha CM, Choi YK, Lee SJ, Ham HJ, Kim BG, Park KG, Park SY, Lee CH, Choi CS, Park TS, Lee WN, Harris RA, Lee IK. Go Y, et al. Among authors: kang hj. Diabetes. 2016 Oct;65(10):2876-87. doi: 10.2337/db16-0223. Epub 2016 Jul 6. Diabetes. 2016. PMID: 27385159
Pyruvate Dehydrogenase Kinase Is a Metabolic Checkpoint for Polarization of Macrophages to the M1 Phenotype.
Min BK, Park S, Kang HJ, Kim DW, Ham HJ, Ha CM, Choi BJ, Lee JY, Oh CJ, Yoo EK, Kim HE, Kim BG, Jeon JH, Hyeon DY, Hwang D, Kim YH, Lee CH, Lee T, Kim JW, Choi YK, Park KG, Chawla A, Lee J, Harris RA, Lee IK. Min BK, et al. Among authors: kang hj. Front Immunol. 2019 May 7;10:944. doi: 10.3389/fimmu.2019.00944. eCollection 2019. Front Immunol. 2019. PMID: 31134063 Free PMC article.
Pyruvate dehydrogenase kinase 1 and 2 deficiency reduces high-fat diet-induced hypertrophic obesity and inhibits the differentiation of preadipocytes into mature adipocytes.
Kang HJ, Min BK, Choi WI, Jeon JH, Kim DW, Park S, Lee YK, Kim HJ, Byeon JE, Go Y, Ham HJ, Jeon YH, Kim MJ, Lee JY, Wende AR, Choi SH, Harris RA, Lee IK. Kang HJ, et al. Exp Mol Med. 2021 Sep;53(9):1390-1401. doi: 10.1038/s12276-021-00672-1. Epub 2021 Sep 22. Exp Mol Med. 2021. PMID: 34552205 Free PMC article.
2,448 results