Kang H - Search Results

1

VDAC oligomers form mitochondrial pores to release mtDNA fragments and promote lupus-like disease.

Kim J, Gupta R, Blanco LP, Yang S, Shteinfer-Kuzmine A, Wang K, Zhu J, Yoon HE, Wang X, Kerkhofs M, Kang H, Brown AL, Park SJ, Xu X, Zandee van Rilland E, Kim MK, Cohen JI, Kaplan MJ, Shoshan-Barmatz V, Chung JH. Kim J, et al. Among authors: kang h. Science. 2019 Dec 20;366(6472):1531-1536. doi: 10.1126/science.aav4011. Epub 2019 Dec 19. Science. 2019. PMID: 31857488 Free PMC article.

2

CK2 is the regulator of SIRT1 substrate-binding affinity, deacetylase activity and cellular response to DNA-damage.

Kang H, Jung JW, Kim MK, Chung JH. Kang H, et al. PLoS One. 2009 Aug 14;4(8):e6611. doi: 10.1371/journal.pone.0006611. PLoS One. 2009. PMID: 19680552 Free PMC article.

3

Specific Sirt1 Activator-mediated Improvement in Glucose Homeostasis Requires Sirt1-Independent Activation of AMPK.

Park SJ, Ahmad F, Um JH, Brown AL, Xu X, Kang H, Ke H, Feng X, Ryall J, Philp A, Schenk S, Kim MK, Sartorelli V, Chung JH. Park SJ, et al. Among authors: kang h. EBioMedicine. 2017 Apr;18:128-138. doi: 10.1016/j.ebiom.2017.03.019. Epub 2017 Mar 14. EBioMedicine. 2017. PMID: 28396013 Free PMC article.

4

AMP-activated protein kinase-deficient mice are resistant to the metabolic effects of resveratrol.

Um JH, Park SJ, Kang H, Yang S, Foretz M, McBurney MW, Kim MK, Viollet B, Chung JH. Um JH, et al. Among authors: kang h. Diabetes. 2010 Mar;59(3):554-63. doi: 10.2337/db09-0482. Epub 2009 Nov 23. Diabetes. 2010. PMID: 19934007 Free PMC article.

5

Promyelocytic leukemia inhibits adipogenesis, and loss of promyelocytic leukemia results in fat accumulation in mice.

Kim MK, Yang S, Lee KH, Um JH, Liu M, Kang H, Park SJ, Chung JH. Kim MK, et al. Among authors: kang h. Am J Physiol Endocrinol Metab. 2011 Dec;301(6):E1130-42. doi: 10.1152/ajpendo.00092.2011. Epub 2011 Aug 16. Am J Physiol Endocrinol Metab. 2011. PMID: 21846906 Free PMC article.

6

Peptide switch is essential for Sirt1 deacetylase activity.

Kang H, Suh JY, Jung YS, Jung JW, Kim MK, Chung JH. Kang H, et al. Mol Cell. 2011 Oct 21;44(2):203-13. doi: 10.1016/j.molcel.2011.07.038. Mol Cell. 2011. PMID: 22017869 Free PMC article.

7

ATR, PML, and CHK2 play a role in arsenic trioxide-induced apoptosis.

Joe Y, Jeong JH, Yang S, Kang H, Motoyama N, Pandolfi PP, Chung JH, Kim MK. Joe Y, et al. Among authors: kang h. J Biol Chem. 2006 Sep 29;281(39):28764-71. doi: 10.1074/jbc.M604392200. Epub 2006 Aug 3. J Biol Chem. 2006. PMID: 16891316 Free article.

8

Activation of 5'-AMP-activated kinase with diabetes drug metformin induces casein kinase Iepsilon (CKIepsilon)-dependent degradation of clock protein mPer2.

Um JH, Yang S, Yamazaki S, Kang H, Viollet B, Foretz M, Chung JH. Um JH, et al. Among authors: kang h. J Biol Chem. 2007 Jul 20;282(29):20794-8. doi: 10.1074/jbc.C700070200. Epub 2007 May 24. J Biol Chem. 2007. PMID: 17525164 Free article.

9

Inactivation of EWS reduces PGC-1α protein stability and mitochondrial homeostasis.

Park JH, Kang HJ, Lee YK, Kang H, Kim J, Chung JH, Chang JS, McPherron AC, Lee SB. Park JH, et al. Among authors: kang h, kang hj. Proc Natl Acad Sci U S A. 2015 May 12;112(19):6074-9. doi: 10.1073/pnas.1504391112. Epub 2015 Apr 27. Proc Natl Acad Sci U S A. 2015. PMID: 25918410 Free PMC article.

10

Sirt1 carboxyl-domain is an ATP-repressible domain that is transferrable to other proteins.

Kang H, Oka S, Lee DY, Park J, Aponte AM, Jung YS, Bitterman J, Zhai P, He Y, Kooshapur H, Ghirlando R, Tjandra N, Lee SB, Kim MK, Sadoshima J, Chung JH. Kang H, et al. Nat Commun. 2017 May 15;8:15560. doi: 10.1038/ncomms15560. Nat Commun. 2017. PMID: 28504272 Free PMC article.

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