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SIRT6 Overexpression Improves Various Aspects of Mouse Healthspan.
Roichman A, Kanfi Y, Glazz R, Naiman S, Amit U, Landa N, Tinman S, Stein I, Pikarsky E, Leor J, Cohen HY. Roichman A, et al. Among authors: kanfi y. J Gerontol A Biol Sci Med Sci. 2017 May 1;72(5):603-615. doi: 10.1093/gerona/glw152. J Gerontol A Biol Sci Med Sci. 2017. PMID: 27519885
The sirtuin SIRT6 regulates lifespan in male mice.
Kanfi Y, Naiman S, Amir G, Peshti V, Zinman G, Nahum L, Bar-Joseph Z, Cohen HY. Kanfi Y, et al. Nature. 2012 Feb 22;483(7388):218-21. doi: 10.1038/nature10815. Nature. 2012. PMID: 22367546
Characterization of physiological defects in adult SIRT6-/- mice.
Peshti V, Obolensky A, Nahum L, Kanfi Y, Rathaus M, Avraham M, Tinman S, Alt FW, Banin E, Cohen HY. Peshti V, et al. Among authors: kanfi y. PLoS One. 2017 Apr 27;12(4):e0176371. doi: 10.1371/journal.pone.0176371. eCollection 2017. PLoS One. 2017. PMID: 28448551 Free PMC article.
Restoration of energy homeostasis by SIRT6 extends healthy lifespan.
Roichman A, Elhanati S, Aon MA, Abramovich I, Di Francesco A, Shahar Y, Avivi MY, Shurgi M, Rubinstein A, Wiesner Y, Shuchami A, Petrover Z, Lebenthal-Loinger I, Yaron O, Lyashkov A, Ubaida-Mohien C, Kanfi Y, Lerrer B, Fernández-Marcos PJ, Serrano M, Gottlieb E, de Cabo R, Cohen HY. Roichman A, et al. Among authors: kanfi y. Nat Commun. 2021 May 28;12(1):3208. doi: 10.1038/s41467-021-23545-7. Nat Commun. 2021. PMID: 34050173 Free PMC article.
Sirtuins as regulators of mammalian aging.
Naiman S, Kanfi Y, Cohen HY. Naiman S, et al. Among authors: kanfi y. Aging (Albany NY). 2012 Aug;4(8):521-2. doi: 10.18632/aging.100478. Aging (Albany NY). 2012. PMID: 22915706 Free PMC article. No abstract available.
SIRT6 exhibits nucleosome-dependent deacetylase activity.
Gil R, Barth S, Kanfi Y, Cohen HY. Gil R, et al. Among authors: kanfi y. Nucleic Acids Res. 2013 Oct;41(18):8537-45. doi: 10.1093/nar/gkt642. Epub 2013 Jul 26. Nucleic Acids Res. 2013. PMID: 23892288 Free PMC article.
Multiple regulatory layers of SREBP1/2 by SIRT6.
Elhanati S, Kanfi Y, Varvak A, Roichman A, Carmel-Gross I, Barth S, Gibor G, Cohen HY. Elhanati S, et al. Among authors: kanfi y. Cell Rep. 2013 Sep 12;4(5):905-12. doi: 10.1016/j.celrep.2013.08.006. Epub 2013 Sep 5. Cell Rep. 2013. PMID: 24012758 Free article.
New Role for Interleukin-13 Receptor α1 in Myocardial Homeostasis and Heart Failure.
Amit U, Kain D, Wagner A, Sahu A, Nevo-Caspi Y, Gonen N, Molotski N, Konfino T, Landa N, Naftali-Shani N, Blum G, Merquiol E, Karo-Atar D, Kanfi Y, Paret G, Munitz A, Cohen HY, Ruppin E, Hannenhalli S, Leor J. Amit U, et al. Among authors: kanfi y. J Am Heart Assoc. 2017 May 20;6(5):e005108. doi: 10.1161/JAHA.116.005108. J Am Heart Assoc. 2017. PMID: 28528324 Free PMC article.
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