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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2006 2
2008 2
2009 2
2010 1
2012 3
2013 1
2014 7
2015 9
2016 7
2017 5
2018 6
2019 5
2020 6
2021 7
2022 8
2023 6
2024 1

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69 results

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Page 1
Discovery of 7-Azanorbornane-Based Dual Agonists for the Delta and Kappa Opioid Receptors through an In Situ Screening Protocol.
Karaki F, Takamori T, Kawakami K, Sakurai S, Hidaka K, Ishii K, Oki T, Sato N, Atsumi N, Ashizawa K, Taguchi A, Ura A, Naruse T, Hirayama S, Nonaka M, Miyano K, Uezono Y, Fujii H. Karaki F, et al. Among authors: miyano k. Molecules. 2023 Oct 3;28(19):6925. doi: 10.3390/molecules28196925. Molecules. 2023. PMID: 37836768 Free PMC article.
Infusions of beta-hydroxybutyrate, an endogenous NLRP3 inflammasome inhibitor, produce antidepressant-like effects on learned helplessness rats through BDNF-TrkB signaling and AMPA receptor activation, and strengthen learning ability.
Shirayama Y, Iwata M, Miyano K, Hirose Y, Oda Y, Fujita Y, Hashimoto K. Shirayama Y, et al. Among authors: miyano k. Brain Res. 2023 Dec 15;1821:148567. doi: 10.1016/j.brainres.2023.148567. Epub 2023 Sep 7. Brain Res. 2023. PMID: 37689333
G protein-biased LPAR1 agonism of prototypic antidepressants: Implication in the identification of novel therapeutic target for depression.
Kajitani N, Okada-Tsuchioka M, Inoue A, Miyano K, Masuda T, Boku S, Iwamoto K, Ohtsuki S, Uezono Y, Aoki J, Takebayashi M. Kajitani N, et al. Among authors: miyano k. Neuropsychopharmacology. 2024 Feb;49(3):561-572. doi: 10.1038/s41386-023-01727-9. Epub 2023 Sep 6. Neuropsychopharmacology. 2024. PMID: 37673966 Free PMC article.
Therapeutic Potential of Orally Administered Rubiscolin-6.
Karasawa Y, Miyano K, Yamaguchi M, Nonaka M, Yamaguchi K, Iseki M, Kawagoe I, Uezono Y. Karasawa Y, et al. Among authors: miyano k. Int J Mol Sci. 2023 Jun 9;24(12):9959. doi: 10.3390/ijms24129959. Int J Mol Sci. 2023. PMID: 37373107 Free PMC article. Review.
Distinct Profiles of Desensitization of µ-Opioid Receptors Caused by Remifentanil or Fentanyl: In Vitro Assay with Cells and Three-Dimensional Structural Analyses.
Uezono E, Mizobuchi Y, Miyano K, Ohbuchi K, Murata H, Komatsu A, Manabe S, Nonaka M, Hirokawa T, Yamaguchi K, Iseki M, Uezono Y, Hayashida M, Kawagoe I. Uezono E, et al. Among authors: miyano k. Int J Mol Sci. 2023 May 6;24(9):8369. doi: 10.3390/ijms24098369. Int J Mol Sci. 2023. PMID: 37176075 Free PMC article.
Evaluation of the Intracellular Signaling Activities of κ-Opioid Receptor Agonists, Nalfurafine Analogs; Focusing on the Selectivity of G-Protein- and β-Arrestin-Mediated Pathways.
Yamaguchi M, Miyano K, Hirayama S, Karasawa Y, Ohshima K, Uezono E, Komatsu A, Nonaka M, Fujii H, Yamaguchi K, Iseki M, Hayashida M, Uezono Y. Yamaguchi M, et al. Among authors: miyano k. Molecules. 2022 Oct 19;27(20):7065. doi: 10.3390/molecules27207065. Molecules. 2022. PMID: 36296658 Free PMC article.
Possible mechanism for improving the endogenous immune system through the blockade of peripheral μ-opioid receptors by treatment with naldemedine.
Gondoh E, Hamada Y, Mori T, Iwazawa Y, Shinohara A, Narita M, Sato D, Tezuka H, Yamauchi T, Tsujimura M, Yoshida S, Tanaka K, Yamashita K, Akatori H, Higashiyama K, Arakawa K, Suda Y, Miyano K, Iseki M, Inada E, Kuzumaki N, Narita M. Gondoh E, et al. Among authors: miyano k. Br J Cancer. 2022 Nov;127(8):1565-1574. doi: 10.1038/s41416-022-01928-x. Epub 2022 Aug 9. Br J Cancer. 2022. PMID: 35945243 Free PMC article.
Novel Opioid Analgesics for the Development of Transdermal Opioid Patches That Possess Morphine-Like Pharmacological Profiles Rather Than Fentanyl: Possible Opioid Switching Alternatives Among Patch Formula.
Komatsu A, Miyano K, Nakayama D, Mizobuchi Y, Uezono E, Ohshima K, Karasawa Y, Kuroda Y, Nonaka M, Yamaguchi K, Iseki M, Uezono Y, Hayashida M. Komatsu A, et al. Among authors: miyano k. Anesth Analg. 2022 May 1;134(5):1082-1093. doi: 10.1213/ANE.0000000000005954. Anesth Analg. 2022. PMID: 35427270 Free PMC article.
69 results