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Total synthesis of (+/-)-garsubellin A.
Kuramochi A, Usuda H, Yamatsugu K, Kanai M, Shibasaki M. Kuramochi A, et al. Among authors: kanai m. J Am Chem Soc. 2005 Oct 19;127(41):14200-1. doi: 10.1021/ja055301t. J Am Chem Soc. 2005. PMID: 16218611
A method for the synthesis of an oseltamivir PET tracer.
Morita M, Sone T, Yamatsugu K, Sohtome Y, Matsunaga S, Kanai M, Watanabe Y, Shibasaki M. Morita M, et al. Among authors: kanai m. Bioorg Med Chem Lett. 2008 Jan 15;18(2):600-2. doi: 10.1016/j.bmcl.2007.11.079. Epub 2007 Nov 28. Bioorg Med Chem Lett. 2008. PMID: 18055200
Oseltamivir enhances hippocampal network synchronization.
Usami A, Sasaki T, Satoh N, Akiba T, Yokoshima S, Fukuyama T, Yamatsugu K, Kanai M, Shibasaki M, Matsuki N, Ikegaya Y. Usami A, et al. Among authors: kanai m. J Pharmacol Sci. 2008 Apr;106(4):659-62. doi: 10.1254/jphs.sc0070467. Epub 2008 Apr 9. J Pharmacol Sci. 2008. PMID: 18403897 Free article.
Limited brain distribution of [3R,4R,5S]-4-acetamido-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate phosphate (Ro 64-0802), a pharmacologically active form of oseltamivir, by active efflux across the blood-brain barrier mediated by organic anion transporter 3 (Oat3/Slc22a8) and multidrug resistance-associated protein 4 (Mrp4/Abcc4).
Ose A, Ito M, Kusuhara H, Yamatsugu K, Kanai M, Shibasaki M, Hosokawa M, Schuetz JD, Sugiyama Y. Ose A, et al. Among authors: kanai m. Drug Metab Dispos. 2009 Feb;37(2):315-21. doi: 10.1124/dmd.108.024018. Epub 2008 Nov 24. Drug Metab Dispos. 2009. PMID: 19029202
Pharmacologic action of oseltamivir on the nervous system.
Ishii K, Hamamoto H, Sasaki T, Ikegaya Y, Yamatsugu K, Kanai M, Shibasaki M, Sekimizu K. Ishii K, et al. Among authors: kanai m. Drug Discov Ther. 2008 Feb;2(1):24-34. Drug Discov Ther. 2008. PMID: 22504452 Free article.
1,329 results