Kanaar R - Search Results

1

A Microfluidic Cancer-on-Chip Platform Predicts Drug Response Using Organotypic Tumor Slice Culture.

Chakrabarty S, Quiros-Solano WF, Kuijten MMP, Haspels B, Mallya S, Lo CSY, Othman A, Silvestri C, van de Stolpe A, Gaio N, Odijk H, van de Ven M, de Ridder CMA, van Weerden WM, Jonkers J, Dekker R, Taneja N, Kanaar R, van Gent DC. Chakrabarty S, et al. Among authors: kanaar r. Cancer Res. 2022 Feb 1;82(3):510-520. doi: 10.1158/0008-5472.CAN-21-0799. Epub 2021 Dec 6. Cancer Res. 2022. PMID: 34872965 Free PMC article.

2

Molecular mechanisms of DNA double strand break repair.

Kanaar R, Hoeijmakers JH, van Gent DC. Kanaar R, et al. Trends Cell Biol. 1998 Dec;8(12):483-9. doi: 10.1016/s0962-8924(98)01383-x. Trends Cell Biol. 1998. PMID: 9861670 Review.

3

DNA-binding and strand-annealing activities of human Mre11: implications for its roles in DNA double-strand break repair pathways.

de Jager M, Dronkert ML, Modesti M, Beerens CE, Kanaar R, van Gent DC. de Jager M, et al. Among authors: kanaar r. Nucleic Acids Res. 2001 Mar 15;29(6):1317-25. doi: 10.1093/nar/29.6.1317. Nucleic Acids Res. 2001. PMID: 11238998 Free PMC article.

4

Chromosomal stability and the DNA double-stranded break connection.

van Gent DC, Hoeijmakers JH, Kanaar R. van Gent DC, et al. Among authors: kanaar r. Nat Rev Genet. 2001 Mar;2(3):196-206. doi: 10.1038/35056049. Nat Rev Genet. 2001. PMID: 11256071 Review.

5

The structure-specific endonuclease Ercc1-Xpf is required for targeted gene replacement in embryonic stem cells.

Niedernhofer LJ, Essers J, Weeda G, Beverloo B, de Wit J, Muijtjens M, Odijk H, Hoeijmakers JH, Kanaar R. Niedernhofer LJ, et al. Among authors: kanaar r. EMBO J. 2001 Nov 15;20(22):6540-9. doi: 10.1093/emboj/20.22.6540. EMBO J. 2001. PMID: 11707424 Free PMC article.

6

Human Rad50/Mre11 is a flexible complex that can tether DNA ends.

de Jager M, van Noort J, van Gent DC, Dekker C, Kanaar R, Wyman C. de Jager M, et al. Among authors: kanaar r. Mol Cell. 2001 Nov;8(5):1129-35. doi: 10.1016/s1097-2765(01)00381-1. Mol Cell. 2001. PMID: 11741547 Free article.

7

DNA end-binding specificity of human Rad50/Mre11 is influenced by ATP.

de Jager M, Wyman C, van Gent DC, Kanaar R. de Jager M, et al. Among authors: kanaar r. Nucleic Acids Res. 2002 Oct 15;30(20):4425-31. doi: 10.1093/nar/gkf574. Nucleic Acids Res. 2002. PMID: 12384589 Free PMC article.

8

Ionizing radiation-induced foci formation of mammalian Rad51 and Rad54 depends on the Rad51 paralogs, but not on Rad52.

van Veelen LR, Essers J, van de Rakt MW, Odijk H, Pastink A, Zdzienicka MZ, Paulusma CC, Kanaar R. van Veelen LR, et al. Among authors: kanaar r. Mutat Res. 2005 Jul 1;574(1-2):34-49. doi: 10.1016/j.mrfmmm.2005.01.020. Epub 2005 Apr 9. Mutat Res. 2005. PMID: 15914205

9

NBS1 cooperates with homologous recombination to counteract chromosome breakage during replication.

Brugmans L, Verkaik NS, Kunen M, van Drunen E, Williams BR, Petrini JH, Kanaar R, Essers J, van Gent DC. Brugmans L, et al. Among authors: kanaar r. DNA Repair (Amst). 2009 Dec 3;8(12):1363-70. doi: 10.1016/j.dnarep.2009.09.002. Epub 2009 Sep 25. DNA Repair (Amst). 2009. PMID: 19782649 Free PMC article.

10

Functional ex vivo assay to select homologous recombination-deficient breast tumors for PARP inhibitor treatment.

Naipal KA, Verkaik NS, Ameziane N, van Deurzen CH, Ter Brugge P, Meijers M, Sieuwerts AM, Martens JW, O'Connor MJ, Vrieling H, Hoeijmakers JH, Jonkers J, Kanaar R, de Winter JP, Vreeswijk MP, Jager A, van Gent DC. Naipal KA, et al. Among authors: kanaar r. Clin Cancer Res. 2014 Sep 15;20(18):4816-26. doi: 10.1158/1078-0432.CCR-14-0571. Epub 2014 Jun 24. Clin Cancer Res. 2014. PMID: 24963051

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