Kanaan NM - Search Results

1

Tau Kinetics in Neurons and the Human Central Nervous System.

Sato C, Barthélemy NR, Mawuenyega KG, Patterson BW, Gordon BA, Jockel-Balsarotti J, Sullivan M, Crisp MJ, Kasten T, Kirmess KM, Kanaan NM, Yarasheski KE, Baker-Nigh A, Benzinger TLS, Miller TM, Karch CM, Bateman RJ. Sato C, et al. Among authors: kanaan nm. Neuron. 2018 Mar 21;97(6):1284-1298.e7. doi: 10.1016/j.neuron.2018.02.015. Neuron. 2018. PMID: 29566794 Free PMC article.

2

Soluble pre-fibrillar tau and β-amyloid species emerge in early human Alzheimer's disease and track disease progression and cognitive decline.

Koss DJ, Jones G, Cranston A, Gardner H, Kanaan NM, Platt B. Koss DJ, et al. Among authors: kanaan nm. Acta Neuropathol. 2016 Dec;132(6):875-895. doi: 10.1007/s00401-016-1632-3. Epub 2016 Oct 21. Acta Neuropathol. 2016. PMID: 27770234 Free PMC article.

3

Tau Kinetics in Neurons and the Human Central Nervous System.

Sato C, Barthélemy NR, Mawuenyega KG, Patterson BW, Gordon BA, Jockel-Balsarotti J, Sullivan M, Crisp MJ, Kasten T, Kirmess KM, Kanaan NM, Yarasheski KE, Baker-Nigh A, Benzinger TLS, Miller TM, Karch CM, Bateman RJ. Sato C, et al. Among authors: kanaan nm. Neuron. 2018 May 16;98(4):861-864. doi: 10.1016/j.neuron.2018.04.035. Neuron. 2018. PMID: 29772204 Free PMC article. No abstract available.

4

Phosphorylation in the amino terminus of tau prevents inhibition of anterograde axonal transport.

Kanaan NM, Morfini G, Pigino G, LaPointe NE, Andreadis A, Song Y, Leitman E, Binder LI, Brady ST. Kanaan NM, et al. Neurobiol Aging. 2012 Apr;33(4):826.e15-30. doi: 10.1016/j.neurobiolaging.2011.06.006. Epub 2011 Jul 27. Neurobiol Aging. 2012. PMID: 21794954 Free PMC article.

5

Progression of tau pathology in cholinergic Basal forebrain neurons in mild cognitive impairment and Alzheimer's disease.

Vana L, Kanaan NM, Ugwu IC, Wuu J, Mufson EJ, Binder LI. Vana L, et al. Among authors: kanaan nm. Am J Pathol. 2011 Nov;179(5):2533-50. doi: 10.1016/j.ajpath.2011.07.044. Epub 2011 Sep 23. Am J Pathol. 2011. PMID: 21945902 Free PMC article.

6

Axonal degeneration in Alzheimer's disease: when signaling abnormalities meet the axonal transport system.

Kanaan NM, Pigino GF, Brady ST, Lazarov O, Binder LI, Morfini GA. Kanaan NM, et al. Exp Neurol. 2013 Aug;246:44-53. doi: 10.1016/j.expneurol.2012.06.003. Epub 2012 Jun 19. Exp Neurol. 2013. PMID: 22721767 Free PMC article. Review.

7

Gene Therapy Models of Alzheimer's Disease and Other Dementias.

Combs B, Kneynsberg A, Kanaan NM. Combs B, et al. Among authors: kanaan nm. Methods Mol Biol. 2016;1382:339-66. doi: 10.1007/978-1-4939-3271-9_25. Methods Mol Biol. 2016. PMID: 26611599 Free PMC article.

8

Pathological conformations involving the amino terminus of tau occur early in Alzheimer's disease and are differentially detected by monoclonal antibodies.

Combs B, Hamel C, Kanaan NM. Combs B, et al. Among authors: kanaan nm. Neurobiol Dis. 2016 Oct;94:18-31. doi: 10.1016/j.nbd.2016.05.016. Epub 2016 May 31. Neurobiol Dis. 2016. PMID: 27260838 Free PMC article.

9

Pseudophosphorylation of tau at S422 enhances SDS-stable dimer formation and impairs both anterograde and retrograde fast axonal transport.

Tiernan CT, Combs B, Cox K, Morfini G, Brady ST, Counts SE, Kanaan NM. Tiernan CT, et al. Among authors: kanaan nm. Exp Neurol. 2016 Sep;283(Pt A):318-29. doi: 10.1016/j.expneurol.2016.06.030. Epub 2016 Jun 30. Exp Neurol. 2016. PMID: 27373205 Free PMC article.

10

Pioglitazone prevents tau oligomerization.

Hamano T, Shirafuji N, Makino C, Yen SH, Kanaan NM, Ueno A, Suzuki J, Ikawa M, Matsunaga A, Yamamura O, Kuriyama M, Nakamoto Y. Hamano T, et al. Among authors: kanaan nm. Biochem Biophys Res Commun. 2016 Sep 23;478(3):1035-42. doi: 10.1016/j.bbrc.2016.08.016. Epub 2016 Aug 16. Biochem Biophys Res Commun. 2016. PMID: 27543203

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