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Protein Quality Control Pathways at the Crossroad of Synucleinopathies.
De Mattos EP, Wentink A, Nussbaum-Krammer C, Hansen C, Bergink S, Melki R, Kampinga HH. De Mattos EP, et al. Among authors: kampinga hh. J Parkinsons Dis. 2020;10(2):369-382. doi: 10.3233/JPD-191790. J Parkinsons Dis. 2020. PMID: 31985474 Free PMC article. Review.
DNAJs: more than substrate delivery to HSPA.
Dekker SL, Kampinga HH, Bergink S. Dekker SL, et al. Among authors: kampinga hh. Front Mol Biosci. 2015 Jun 30;2:35. doi: 10.3389/fmolb.2015.00035. eCollection 2015. Front Mol Biosci. 2015. PMID: 26176011 Free PMC article. Review.
The S/T-Rich Motif in the DNAJB6 Chaperone Delays Polyglutamine Aggregation and the Onset of Disease in a Mouse Model.
Kakkar V, Månsson C, de Mattos EP, Bergink S, van der Zwaag M, van Waarde MAWH, Kloosterhuis NJ, Melki R, van Cruchten RTP, Al-Karadaghi S, Arosio P, Dobson CM, Knowles TPJ, Bates GP, van Deursen JM, Linse S, van de Sluis B, Emanuelsson C, Kampinga HH. Kakkar V, et al. Among authors: kampinga hh. Mol Cell. 2016 Apr 21;62(2):272-283. doi: 10.1016/j.molcel.2016.03.017. Epub 2016 Apr 14. Mol Cell. 2016. PMID: 27151442 Free article.
Chaperones in Polyglutamine Aggregation: Beyond the Q-Stretch.
Kuiper EF, de Mattos EP, Jardim LB, Kampinga HH, Bergink S. Kuiper EF, et al. Among authors: kampinga hh. Front Neurosci. 2017 Mar 23;11:145. doi: 10.3389/fnins.2017.00145. eCollection 2017. Front Neurosci. 2017. PMID: 28386214 Free PMC article. Review.
Myopathy associated BAG3 mutations lead to protein aggregation by stalling Hsp70 networks.
Meister-Broekema M, Freilich R, Jagadeesan C, Rauch JN, Bengoechea R, Motley WW, Kuiper EFE, Minoia M, Furtado GV, van Waarde MAWH, Bird SJ, Rebelo A, Zuchner S, Pytel P, Scherer SS, Morelli FF, Carra S, Weihl CC, Bergink S, Gestwicki JE, Kampinga HH. Meister-Broekema M, et al. Among authors: kampinga hh. Nat Commun. 2018 Dec 17;9(1):5342. doi: 10.1038/s41467-018-07718-5. Nat Commun. 2018. PMID: 30559338 Free PMC article.
228 results