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Year Number of Results
2018 2
2019 2
2020 6
2021 3
2022 3
2023 2
2024 0

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17 results

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Page 1
Discovery of novel multifunctional ligands targeting GABA transporters, butyrylcholinesterase, β-secretase, and amyloid β aggregation as potential treatment of Alzheimer's disease.
Zaręba P, Łątka K, Mazur G, Gryzło B, Pasieka A, Godyń J, Panek D, Skrzypczak-Wiercioch A, Höfner GC, Latacz G, Maj M, Espargaró A, Sabaté R, Jóźwiak K, Wanner KT, Sałat K, Malawska B, Kulig K, Bajda M. Zaręba P, et al. Among authors: latka k. Eur J Med Chem. 2023 Dec 5;261:115832. doi: 10.1016/j.ejmech.2023.115832. Epub 2023 Oct 7. Eur J Med Chem. 2023. PMID: 37837674 Free article.
New cyclopentaquinoline and 3,5-dichlorobenzoic acid hybrids with neuroprotection against oxidative stress for the treatment of Alzheimer's disease.
Czarnecka K, Girek M, Kręcisz P, Skibiński R, Łątka K, Jończyk J, Bajda M, Szymczyk P, Galita G, Kabziński J, Majsterek I, Espargaró A, Sabate R, Szymański P. Czarnecka K, et al. Among authors: latka k. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2158822. doi: 10.1080/14756366.2022.2158822. J Enzyme Inhib Med Chem. 2023. PMID: 36629422 Free PMC article.
Discovery of the First Highly Selective Antagonist of the GluK3 Kainate Receptor Subtype.
Chałupnik P, Vialko A, Pickering DS, Hinkkanen M, Donbosco S, Møller TC, Jensen AA, Nielsen B, Bay Y, Kristensen AS, Johansen TN, Łątka K, Bajda M, Szymańska E. Chałupnik P, et al. Among authors: latka k. Int J Mol Sci. 2022 Aug 8;23(15):8797. doi: 10.3390/ijms23158797. Int J Mol Sci. 2022. PMID: 35955932 Free PMC article.
Development of tricyclic N-benzyl-4-hydroxybutanamide derivatives as inhibitors of GABA transporters mGAT1-4 with anticonvulsant, antinociceptive, and antidepressant activity.
Zaręba P, Sałat K, Höfner GC, Łątka K, Bajda M, Latacz G, Kotniewicz K, Rapacz A, Podkowa A, Maj M, Jóźwiak K, Filipek B, Wanner KT, Malawska B, Kulig K. Zaręba P, et al. Among authors: latka k. Eur J Med Chem. 2021 Oct 5;221:113512. doi: 10.1016/j.ejmech.2021.113512. Epub 2021 May 4. Eur J Med Chem. 2021. PMID: 34015586
Pyridinium-2-carbaldoximes with quinolinium carboxamide moiety are simultaneous reactivators of acetylcholinesterase and butyrylcholinesterase inhibited by nerve agent surrogates.
Lee HM, Andrys R, Jonczyk J, Kim K, Vishakantegowda AG, Malinak D, Skarka A, Schmidt M, Vaskova M, Latka K, Bajda M, Jung YS, Malawska B, Musilek K. Lee HM, et al. Among authors: latka k. J Enzyme Inhib Med Chem. 2021 Dec;36(1):437-449. doi: 10.1080/14756366.2020.1869954. J Enzyme Inhib Med Chem. 2021. PMID: 33467931 Free PMC article.
Corrigendum to "Search for new multi-target compounds against Alzheimer's disease among histamine H3 receptor ligands" [Eur. J. Med. Chem. 185 (2020) 111785].
Bajda M, Łażewska D, Godyń J, Zaręba P, Kuder K, Hagenow S, Łątka K, Stawarska E, Stark H, Kieć-Kononowicz K, Malawska B. Bajda M, et al. Among authors: latka k. Eur J Med Chem. 2020 Nov 1;205:112611. doi: 10.1016/j.ejmech.2020.112611. Epub 2020 Aug 10. Eur J Med Chem. 2020. PMID: 32791398 No abstract available.
New Tetrahydroacridine Hybrids with Dichlorobenzoic Acid Moiety Demonstrating Multifunctional Potential for the Treatment of Alzheimer's Disease.
Czarnecka K, Girek M, Wójtowicz P, Kręcisz P, Skibiński R, Jończyk J, Łątka K, Bajda M, Walczak A, Galita G, Kabziński J, Majsterek I, Szymczyk P, Szymański P. Czarnecka K, et al. Among authors: latka k. Int J Mol Sci. 2020 May 26;21(11):3765. doi: 10.3390/ijms21113765. Int J Mol Sci. 2020. PMID: 32466601 Free PMC article.
17 results