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Targeting tumor-associated macrophages with anti-CSF-1R antibody reveals a strategy for cancer therapy.
Ries CH, Cannarile MA, Hoves S, Benz J, Wartha K, Runza V, Rey-Giraud F, Pradel LP, Feuerhake F, Klaman I, Jones T, Jucknischke U, Scheiblich S, Kaluza K, Gorr IH, Walz A, Abiraj K, Cassier PA, Sica A, Gomez-Roca C, de Visser KE, Italiano A, Le Tourneau C, Delord JP, Levitsky H, Blay JY, Rüttinger D. Ries CH, et al. Among authors: kaluza k. Cancer Cell. 2014 Jun 16;25(6):846-59. doi: 10.1016/j.ccr.2014.05.016. Epub 2014 Jun 2. Cancer Cell. 2014. PMID: 24898549 Free article.
A novel angiopoietin-2 selective fully human antibody with potent anti-tumoral and anti-angiogenic efficacy and superior side effect profile compared to Pan-Angiopoietin-1/-2 inhibitors.
Thomas M, Kienast Y, Scheuer W, Bähner M, Kaluza K, Gassner C, Herting F, Brinkmann U, Seeber S, Kavlie A, Welschof M, Ries S, Weidner KM, Regula JT, Klein C. Thomas M, et al. Among authors: kaluza k. PLoS One. 2013;8(2):e54923. doi: 10.1371/journal.pone.0054923. Epub 2013 Feb 6. PLoS One. 2013. PMID: 23405099 Free PMC article.
Allosteric antibody inhibition of human hepsin protease.
Koschubs T, Dengl S, Dürr H, Kaluza K, Georges G, Hartl C, Jennewein S, Lanzendörfer M, Auer J, Stern A, Huang KS, Packman K, Gubler U, Kostrewa D, Ries S, Hansen S, Kohnert U, Cramer P, Mundigl O. Koschubs T, et al. Among authors: kaluza k. Biochem J. 2012 Mar 15;442(3):483-94. doi: 10.1042/BJ20111317. Biochem J. 2012. PMID: 22132769
A robust high throughput platform to generate functional recombinant monoclonal antibodies using rabbit B cells from peripheral blood.
Seeber S, Ros F, Thorey I, Tiefenthaler G, Kaluza K, Lifke V, Fischer JA, Klostermann S, Endl J, Kopetzki E, Pashine A, Siewe B, Kaluza B, Platzer J, Offner S. Seeber S, et al. Among authors: kaluza b, kaluza k. PLoS One. 2014 Feb 4;9(2):e86184. doi: 10.1371/journal.pone.0086184. eCollection 2014. PLoS One. 2014. PMID: 24503933 Free PMC article.
Rabbits transgenic for human IgG genes recapitulating rabbit B-cell biology to generate human antibodies of high specificity and affinity.
Ros F, Offner S, Klostermann S, Thorey I, Niersbach H, Breuer S, Zarnt G, Lorenz S, Puels J, Siewe B, Schueler N, Dragicevic T, Ostler D, Hansen-Wester I, Lifke V, Kaluza B, Kaluza K, van Schooten W, Buelow R, Tissot AC, Platzer J. Ros F, et al. Among authors: kaluza k. MAbs. 2020 Jan-Dec;12(1):1846900. doi: 10.1080/19420862.2020.1846900. MAbs. 2020. PMID: 33228444 Free PMC article.
Multi-platform quantitation of alpha-synuclein human brain proteoforms suggests disease-specific biochemical profiles of synucleinopathies.
Moors TE, Mona D, Luehe S, Duran-Pacheco G, Spycher L, Mundigl O, Kaluza K, Huber S, Hug MN, Kremer T, Ritter M, Dziadek S, Dernick G, van de Berg WDJ, Britschgi M. Moors TE, et al. Among authors: kaluza k. Acta Neuropathol Commun. 2022 Jun 3;10(1):82. doi: 10.1186/s40478-022-01382-z. Acta Neuropathol Commun. 2022. PMID: 35659116 Free PMC article.
The subcellular arrangement of alpha-synuclein proteoforms in the Parkinson's disease brain as revealed by multicolor STED microscopy.
Moors TE, Maat CA, Niedieker D, Mona D, Petersen D, Timmermans-Huisman E, Kole J, El-Mashtoly SF, Spycher L, Zago W, Barbour R, Mundigl O, Kaluza K, Huber S, Hug MN, Kremer T, Ritter M, Dziadek S, Geurts JJG, Gerwert K, Britschgi M, van de Berg WDJ. Moors TE, et al. Among authors: kaluza k. Acta Neuropathol. 2021 Sep;142(3):423-448. doi: 10.1007/s00401-021-02329-9. Epub 2021 Jun 11. Acta Neuropathol. 2021. PMID: 34115198 Free PMC article.
Expression-level dependent activation of recombinant human parathyroid hormone/parathyroid hormone-related peptide receptor: effect of human parathyroid hormone (1-34), (1-31), and (28-48).
Tonn O, Kriegbaum S, Braitmaier A, Schäfer W, Esswein A, Dony C, Kaluza K, Honold K. Tonn O, et al. Among authors: kaluza k. J Recept Signal Transduct Res. 2000 May-Aug;20(2-3):133-51. doi: 10.3109/10799890009150641. J Recept Signal Transduct Res. 2000. PMID: 10994650
43 results