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Norovirus evolution in immunodeficient mice reveals potentiated pathogenicity via a single nucleotide change in the viral capsid.
Walker FC, Hassan E, Peterson ST, Rodgers R, Schriefer LA, Thompson CE, Li Y, Kalugotla G, Blum-Johnston C, Lawrence D, McCune BT, Graziano VR, Lushniak L, Lee S, Roth AN, Karst SM, Nice TJ, Miner JJ, Wilen CB, Baldridge MT. Walker FC, et al. Among authors: kalugotla g. PLoS Pathog. 2021 Mar 11;17(3):e1009402. doi: 10.1371/journal.ppat.1009402. eCollection 2021 Mar. PLoS Pathog. 2021. PMID: 33705489 Free PMC article.
Murine astrovirus tropism for goblet cells and enterocytes facilitates an IFN-λ response in vivo and in enteroid cultures.
Ingle H, Hassan E, Gawron J, Mihi B, Li Y, Kennedy EA, Kalugotla G, Makimaa H, Lee S, Desai P, McDonald KG, Diamond MS, Newberry RD, Good M, Baldridge MT. Ingle H, et al. Among authors: kalugotla g. Mucosal Immunol. 2021 May;14(3):751-761. doi: 10.1038/s41385-021-00387-6. Epub 2021 Mar 5. Mucosal Immunol. 2021. PMID: 33674763 Free PMC article.
STING-associated lung disease in mice relies on T cells but not type I interferon.
Luksch H, Stinson WA, Platt DJ, Qian W, Kalugotla G, Miner CA, Bennion BG, Gerbaulet A, Rösen-Wolff A, Miner JJ. Luksch H, et al. Among authors: kalugotla g. J Allergy Clin Immunol. 2019 Jul;144(1):254-266.e8. doi: 10.1016/j.jaci.2019.01.044. Epub 2019 Feb 14. J Allergy Clin Immunol. 2019. PMID: 30772497 Free PMC article.