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SARS-CoV-2 in severe COVID-19 induces a TGF-β-dominated chronic immune response that does not target itself.
Ferreira-Gomes M, Kruglov A, Durek P, Heinrich F, Tizian C, Heinz GA, Pascual-Reguant A, Du W, Mothes R, Fan C, Frischbutter S, Habenicht K, Budzinski L, Ninnemann J, Jani PK, Guerra GM, Lehmann K, Matz M, Ostendorf L, Heiberger L, Chang HD, Bauherr S, Maurer M, Schönrich G, Raftery M, Kallinich T, Mall MA, Angermair S, Treskatsch S, Dörner T, Corman VM, Diefenbach A, Volk HD, Elezkurtaj S, Winkler TH, Dong J, Hauser AE, Radbruch H, Witkowski M, Melchers F, Radbruch A, Mashreghi MF. Ferreira-Gomes M, et al. Among authors: kallinich t. Nat Commun. 2021 Mar 30;12(1):1961. doi: 10.1038/s41467-021-22210-3. Nat Commun. 2021. PMID: 33785765 Free PMC article.
Regulation of Fatty Acid Oxidation by Twist 1 in the Metabolic Adaptation of T Helper Lymphocytes to Chronic Inflammation.
Hradilkova K, Maschmeyer P, Westendorf K, Schliemann H, Husak O, von Stuckrad ASL, Kallinich T, Minden K, Durek P, Grün JR, Chang HD, Radbruch A. Hradilkova K, et al. Among authors: kallinich t. Arthritis Rheumatol. 2019 Oct;71(10):1756-1765. doi: 10.1002/art.40939. Epub 2019 Sep 5. Arthritis Rheumatol. 2019. PMID: 31131995 Free PMC article.
Antigen-driven PD-1+ TOX+ BHLHE40+ and PD-1+ TOX+ EOMES+ T lymphocytes regulate juvenile idiopathic arthritis in situ.
Maschmeyer P, Heinz GA, Skopnik CM, Lutter L, Mazzoni A, Heinrich F, von Stuckrad SL, Wirth LE, Tran CL, Riedel R, Lehmann K, Sakwa I, Cimaz R, Giudici F, Mall MA, Enghard P, Vastert B, Chang HD, Durek P, Annunziato F, van Wijk F, Radbruch A, Kallinich T, Mashreghi MF. Maschmeyer P, et al. Among authors: kallinich t. Eur J Immunol. 2021 Apr;51(4):915-929. doi: 10.1002/eji.202048797. Epub 2021 Feb 2. Eur J Immunol. 2021. PMID: 33296081 Free article.
Untimely TGFβ responses in COVID-19 limit antiviral functions of NK cells.
Witkowski M, Tizian C, Ferreira-Gomes M, Niemeyer D, Jones TC, Heinrich F, Frischbutter S, Angermair S, Hohnstein T, Mattiola I, Nawrath P, McEwen S, Zocche S, Viviano E, Heinz GA, Maurer M, Kölsch U, Chua RL, Aschman T, Meisel C, Radke J, Sawitzki B, Roehmel J, Allers K, Moos V, Schneider T, Hanitsch L, Mall MA, Conrad C, Radbruch H, Duerr CU, Trapani JA, Marcenaro E, Kallinich T, Corman VM, Kurth F, Sander LE, Drosten C, Treskatsch S, Durek P, Kruglov A, Radbruch A, Mashreghi MF, Diefenbach A. Witkowski M, et al. Among authors: kallinich t. Nature. 2021 Dec;600(7888):295-301. doi: 10.1038/s41586-021-04142-6. Epub 2021 Oct 25. Nature. 2021. PMID: 34695836
[How T lymphocytes coordinate rheumatic inflammation].
Chang HD, Radbruch A, Kallinich T, Mashreghi MF, Hegazy AN, Kruglov A, Nedospasov S, Baumgrass R. Chang HD, et al. Among authors: kallinich t. Z Rheumatol. 2022 Oct;81(8):635-641. doi: 10.1007/s00393-022-01186-5. Epub 2022 Apr 5. Z Rheumatol. 2022. PMID: 35380250 Review. German.
Viral infections in hospitalized children in Germany during the COVID-19 pandemic: Association with non-pharmaceutical interventions.
Terliesner N, Unterwalder N, Edelmann A, Corman V, Knaust A, Rosenfeld L, Gratopp A, Ringe H, Martin L, von Bernuth H, Mall MA, Kallinich T. Terliesner N, et al. Among authors: kallinich t. Front Pediatr. 2022 Aug 11;10:935483. doi: 10.3389/fped.2022.935483. eCollection 2022. Front Pediatr. 2022. PMID: 36034546 Free PMC article.
UNC93B1 variants underlie TLR7-dependent autoimmunity.
Wolf C, Lim EL, Mokhtari M, Kind B, Odainic A, Lara-Villacanas E, Koss S, Mages S, Menzel K, Engel K, Dückers G, Bernbeck B, Schneider DT, Siepermann K, Niehues T, Goetzke CC, Durek P, Minden K, Dörner T, Stittrich A, Szelinski F, Guerra GM, Massoud M, Bieringer M, de Oliveira Mann CC, Beltrán E, Kallinich T, Mashreghi MF, Schmidt SV, Latz E, Klughammer J, Majer O, Lee-Kirsch MA. Wolf C, et al. Among authors: kallinich t. Sci Immunol. 2024 Feb 23;9(92):eadi9769. doi: 10.1126/sciimmunol.adi9769. Epub 2024 Feb 23. Sci Immunol. 2024. PMID: 38207055
133 results