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A dual role for hepatocyte-intrinsic canonical NF-κB signaling in virus control.
Namineni S, O'Connor T, Faure-Dupuy S, Johansen P, Riedl T, Liu K, Xu H, Singh I, Shinde P, Li F, Pandyra A, Sharma P, Ringelhan M, Muschaweckh A, Borst K, Blank P, Lampl S, Neuhaus K, Durantel D, Farhat R, Weber A, Lenggenhager D, Kündig TM, Staeheli P, Protzer U, Wohlleber D, Holzmann B, Binder M, Breuhahn K, Assmus LM, Nattermann J, Abdullah Z, Rolland M, Dejardin E, Lang PA, Lang KS, Karin M, Lucifora J, Kalinke U, Knolle PA, Heikenwalder M. Namineni S, et al. Among authors: kalinke u. J Hepatol. 2020 May;72(5):960-975. doi: 10.1016/j.jhep.2019.12.019. Epub 2020 Jan 15. J Hepatol. 2020. PMID: 31954207 Free article.
Virally infected mouse liver endothelial cells trigger CD8+ T-cell immunity.
Kern M, Popov A, Scholz K, Schumak B, Djandji D, Limmer A, Eggle D, Sacher T, Zawatzky R, Holtappels R, Reddehase MJ, Hartmann G, Debey-Pascher S, Diehl L, Kalinke U, Koszinowski U, Schultze J, Knolle PA. Kern M, et al. Among authors: kalinke u. Gastroenterology. 2010 Jan;138(1):336-46. doi: 10.1053/j.gastro.2009.08.057. Epub 2009 Sep 6. Gastroenterology. 2010. PMID: 19737567
Tissue macrophages suppress viral replication and prevent severe immunopathology in an interferon-I-dependent manner in mice.
Lang PA, Recher M, Honke N, Scheu S, Borkens S, Gailus N, Krings C, Meryk A, Kulawik A, Cervantes-Barragan L, Van Rooijen N, Kalinke U, Ludewig B, Hengartner H, Harris N, Häussinger D, Ohashi PS, Zinkernagel RM, Lang KS. Lang PA, et al. Among authors: kalinke u. Hepatology. 2010 Jul;52(1):25-32. doi: 10.1002/hep.23640. Hepatology. 2010. PMID: 20578253
Expression of type I interferon by splenic macrophages suppresses adaptive immunity during sepsis.
Schwandt T, Schumak B, Gielen GH, Jüngerkes F, Schmidbauer P, Klocke K, Staratschek-Jox A, van Rooijen N, Kraal G, Ludwig-Portugall I, Franken L, Wehner S, Kalff JC, Weber O, Kirschning C, Coch C, Kalinke U, Wenzel J, Kurts C, Zawatzky R, Holzmann B, Layland L, Schultze JL, Burgdorf S, den Haan JM, Knolle PA, Limmer A. Schwandt T, et al. Among authors: kalinke u. EMBO J. 2012 Jan 4;31(1):201-13. doi: 10.1038/emboj.2011.380. Epub 2011 Oct 28. EMBO J. 2012. PMID: 22036947 Free PMC article.
A frequent hypofunctional IRAK2 variant is associated with reduced spontaneous hepatitis C virus clearance.
Wang H, El Maadidi S, Fischer J, Grabski E, Dickhöfer S, Klimosch S, Flannery SM, Filomena A, Wolz OO, Schneiderhan-Marra N, Löffler MW, Wiese M, Pichulik T, Müllhaupt B, Semela D, Dufour JF, Bochud PY, Bowie AG, Kalinke U, Berg T, Weber AN; East-German and Swiss Hepatitis C Virus Study Groups. Wang H, et al. Among authors: kalinke u. Hepatology. 2015 Nov;62(5):1375-87. doi: 10.1002/hep.28105. Epub 2015 Sep 28. Hepatology. 2015. PMID: 26250868
251 results