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Loss of Cdk2 and cyclin A2 impairs cell proliferation and tumorigenesis.
Gopinathan L, Tan SL, Padmakumar VC, Coppola V, Tessarollo L, Kaldis P. Gopinathan L, et al. Among authors: kaldis p. Cancer Res. 2014 Jul 15;74(14):3870-9. doi: 10.1158/0008-5472.CAN-13-3440. Epub 2014 May 6. Cancer Res. 2014. PMID: 24802190 Free PMC article.
Cyclin A2 regulates erythrocyte morphology and numbers.
Jayapal SR, Ang HY, Wang CQ, Bisteau X, Caldez MJ, Xuan GX, Yu W, Tergaonkar V, Osato M, Lim B, Kaldis P. Jayapal SR, et al. Among authors: kaldis p. Cell Cycle. 2016 Nov 16;15(22):3070-3081. doi: 10.1080/15384101.2016.1234546. Epub 2016 Sep 22. Cell Cycle. 2016. PMID: 27657745 Free PMC article.
CDK2 kinase activity is a regulator of male germ cell fate.
Singh P, Patel RK, Palmer N, Grenier JK, Paduch D, Kaldis P, Grimson A, Schimenti JC. Singh P, et al. Among authors: kaldis p. Development. 2019 Nov 6;146(21):dev180273. doi: 10.1242/dev.180273. Development. 2019. PMID: 31582414 Free PMC article.
Less-well known functions of cyclin/CDK complexes.
Palmer N, Kaldis P. Palmer N, et al. Among authors: kaldis p. Semin Cell Dev Biol. 2020 Nov;107:54-62. doi: 10.1016/j.semcdb.2020.04.003. Epub 2020 May 5. Semin Cell Dev Biol. 2020. PMID: 32386818 Free article. Review.
150 results