Kalainayakan SP - Search Results

1

Cyclopamine tartrate, a modulator of hedgehog signaling and mitochondrial respiration, effectively arrests lung tumor growth and progression.

Kalainayakan SP, Ghosh P, Dey S, Fitzgerald KE, Sohoni S, Konduri PC, Garrossian M, Liu L, Zhang L. Kalainayakan SP, et al. Sci Rep. 2019 Feb 5;9(1):1405. doi: 10.1038/s41598-018-38345-1. Sci Rep. 2019. PMID: 30723259 Free PMC article.

2

Cyclopamine tartrate, an inhibitor of Hedgehog signaling, strongly interferes with mitochondrial function and suppresses aerobic respiration in lung cancer cells.

Alam MM, Sohoni S, Kalainayakan SP, Garrossian M, Zhang L. Alam MM, et al. Among authors: kalainayakan sp. BMC Cancer. 2016 Feb 24;16:150. doi: 10.1186/s12885-016-2200-x. BMC Cancer. 2016. PMID: 26911235 Free PMC article.

3

Elevated Heme Synthesis and Uptake Underpin Intensified Oxidative Metabolism and Tumorigenic Functions in Non-Small Cell Lung Cancer Cells.

Sohoni S, Ghosh P, Wang T, Kalainayakan SP, Vidal C, Dey S, Konduri PC, Zhang L. Sohoni S, et al. Among authors: kalainayakan sp. Cancer Res. 2019 May 15;79(10):2511-2525. doi: 10.1158/0008-5472.CAN-18-2156. Epub 2019 Mar 22. Cancer Res. 2019. PMID: 30902795

4

Heme Sequestration Effectively Suppresses the Development and Progression of Both Lung Adenocarcinoma and Squamous Cell Carcinoma.

Dey S, Ashrafi A, Vidal C, Jain N, Kalainayakan SP, Ghosh P, Alemi PS, Salamat N, Konduri PC, Kim JW, Zhang L. Dey S, et al. Among authors: kalainayakan sp. Mol Cancer Res. 2022 Jan;20(1):139-149. doi: 10.1158/1541-7786.MCR-21-0385. Epub 2021 Oct 11. Mol Cancer Res. 2022. PMID: 34635508

5

The vascular disrupting agent combretastatin A-4 phosphate causes prolonged elevation of proteins involved in heme flux and function in resistant tumor cells.

Dey S, Kumari S, Kalainayakan SP, Campbell J 3rd, Ghosh P, Zhou H, FitzGerald KE, Li M, Mason RP, Zhang L, Liu L. Dey S, et al. Among authors: kalainayakan sp. Oncotarget. 2017 Dec 28;9(3):4090-4101. doi: 10.18632/oncotarget.23734. eCollection 2018 Jan 9. Oncotarget. 2017. PMID: 29423106 Free PMC article.

6

Essential roles of mitochondrial and heme function in lung cancer bioenergetics and tumorigenesis.

Kalainayakan SP, FitzGerald KE, Konduri PC, Vidal C, Zhang L. Kalainayakan SP, et al. Cell Biosci. 2018 Nov 2;8:56. doi: 10.1186/s13578-018-0257-8. eCollection 2018. Cell Biosci. 2018. PMID: 30410721 Free PMC article. Review.

7

Hypothalamic PGC-1α protects against high-fat diet exposure by regulating ERα.

Morselli E, Fuente-Martin E, Finan B, Kim M, Frank A, Garcia-Caceres C, Navas CR, Gordillo R, Neinast M, Kalainayakan SP, Li DL, Gao Y, Yi CX, Hahner L, Palmer BF, Tschöp MH, Clegg DJ. Morselli E, et al. Among authors: kalainayakan sp. Cell Rep. 2014 Oct 23;9(2):633-45. doi: 10.1016/j.celrep.2014.09.025. Epub 2014 Oct 16. Cell Rep. 2014. PMID: 25373903 Free PMC article.

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