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Dried blood spot-based newborn screening for bile acid synthesis disorders, Zellweger spectrum disorder, and Niemann-Pick type C1 by detection of bile acid metabolites.
Muto Y, Suzuki M, Takei H, Saito N, Mori J, Sugimoto S, Imagawa K, Nambu R, Oguri S, Itonaga T, Ihara K, Hayashi H, Murayama K, Kakiyama G, Nittono H, Shimizu T. Muto Y, et al. Among authors: kakiyama g. Mol Genet Metab. 2023 Sep-Oct;140(1-2):107703. doi: 10.1016/j.ymgme.2023.107703. Epub 2023 Sep 28. Mol Genet Metab. 2023. PMID: 37802748
Modulation of the fecal bile acid profile by gut microbiota in cirrhosis.
Kakiyama G, Pandak WM, Gillevet PM, Hylemon PB, Heuman DM, Daita K, Takei H, Muto A, Nittono H, Ridlon JM, White MB, Noble NA, Monteith P, Fuchs M, Thacker LR, Sikaroodi M, Bajaj JS. Kakiyama G, et al. J Hepatol. 2013 May;58(5):949-55. doi: 10.1016/j.jhep.2013.01.003. Epub 2013 Jan 16. J Hepatol. 2013. PMID: 23333527 Free PMC article.
LC/ESI-MS/MS analysis of urinary 3β-sulfooxy-7β-N-acetylglucosaminyl-5-cholen-24-oic acid and its amides: new biomarkers for the detection of Niemann-Pick type C disease.
Maekawa M, Misawa Y, Sotoura A, Yamaguchi H, Togawa M, Ohno K, Nittono H, Kakiyama G, Iida T, Hofmann AF, Goto J, Shimada M, Mano N. Maekawa M, et al. Among authors: kakiyama g. Steroids. 2013 Oct;78(10):967-72. doi: 10.1016/j.steroids.2013.05.017. Epub 2013 Jun 7. Steroids. 2013. PMID: 23751200
Colonic inflammation and secondary bile acids in alcoholic cirrhosis.
Kakiyama G, Hylemon PB, Zhou H, Pandak WM, Heuman DM, Kang DJ, Takei H, Nittono H, Ridlon JM, Fuchs M, Gurley EC, Wang Y, Liu R, Sanyal AJ, Gillevet PM, Bajaj JS. Kakiyama G, et al. Am J Physiol Gastrointest Liver Physiol. 2014 Jun 1;306(11):G929-37. doi: 10.1152/ajpgi.00315.2013. Epub 2014 Apr 3. Am J Physiol Gastrointest Liver Physiol. 2014. PMID: 24699327 Free PMC article.
Rifaximin Exerts Beneficial Effects Independent of its Ability to Alter Microbiota Composition.
Kang DJ, Kakiyama G, Betrapally NS, Herzog J, Nittono H, Hylemon PB, Zhou H, Carroll I, Yang J, Gillevet PM, Jiao C, Takei H, Pandak WM, Iida T, Heuman DM, Fan S, Fiehn O, Kurosawa T, Sikaroodi M, Sartor RB, Bajaj JS. Kang DJ, et al. Among authors: kakiyama g. Clin Transl Gastroenterol. 2016 Aug 25;7(8):e187. doi: 10.1038/ctg.2016.44. Clin Transl Gastroenterol. 2016. PMID: 27560928 Free PMC article.
Continued Alcohol Misuse in Human Cirrhosis is Associated with an Impaired Gut-Liver Axis.
Bajaj JS, Kakiyama G, Zhao D, Takei H, Fagan A, Hylemon P, Zhou H, Pandak WM, Nittono H, Fiehn O, Salzman N, Holtz M, Simpson P, Gavis EA, Heuman DM, Liu R, Kang DJ, Sikaroodi M, Gillevet PM. Bajaj JS, et al. Among authors: kakiyama g. Alcohol Clin Exp Res. 2017 Nov;41(11):1857-1865. doi: 10.1111/acer.13498. Epub 2017 Oct 11. Alcohol Clin Exp Res. 2017. PMID: 28925102
Gut microbial composition can differentially regulate bile acid synthesis in humanized mice.
Kang DJ, Hylemon PB, Gillevet PM, Sartor RB, Betrapally NS, Kakiyama G, Sikaroodi M, Takei H, Nittono H, Zhou H, Pandak WM, Yang J, Jiao C, Li X, Lippman HR, Heuman DM, Bajaj JS. Kang DJ, et al. Among authors: kakiyama g. Hepatol Commun. 2017 Feb 27;1(1):61-70. doi: 10.1002/hep4.1020. eCollection 2017 Feb. Hepatol Commun. 2017. PMID: 29404434 Free PMC article.
Alterations in gut microbial function following liver transplant.
Bajaj JS, Kakiyama G, Cox IJ, Nittono H, Takei H, White M, Fagan A, Gavis EA, Heuman DM, Gilles HC, Hylemon P, Taylor-Robinson SD, Legido-Quigley C, Kim M, Xu J, Williams R, Sikaroodi M, Pandak WM, Gillevet PM. Bajaj JS, et al. Among authors: kakiyama g. Liver Transpl. 2018 Jun;24(6):752-761. doi: 10.1002/lt.25046. Epub 2018 May 13. Liver Transpl. 2018. PMID: 29500907 Free PMC article.
Antibiotic-Associated Disruption of Microbiota Composition and Function in Cirrhosis Is Restored by Fecal Transplant.
Bajaj JS, Kakiyama G, Savidge T, Takei H, Kassam ZA, Fagan A, Gavis EA, Pandak WM, Nittono H, Hylemon PB, Boonma P, Haag A, Heuman DM, Fuchs M, John B, Sikaroodi M, Gillevet PM. Bajaj JS, et al. Among authors: kakiyama g. Hepatology. 2018 Oct;68(4):1549-1558. doi: 10.1002/hep.30037. Epub 2018 Sep 20. Hepatology. 2018. PMID: 29665102 Clinical Trial.
57 results