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In vivo and in vitro antimalarial effect and toxicological evaluation of the chloroquine analogue PQUI08001/06.
Reis PA, Pais KC, Pereira MF, Douradinha B, Costa NF, Kaiser CR, Bozza PT, Areas ALL, Zalis MG, de Lima Ferreira M, de Souza MVN, da Silva Frutuoso V, de Castro-Faria-Neto HC. Reis PA, et al. Among authors: kaiser cr. Parasitol Res. 2018 Nov;117(11):3585-3590. doi: 10.1007/s00436-018-6057-6. Epub 2018 Aug 25. Parasitol Res. 2018. PMID: 30145706
N-(2-(arylmethylimino)ethyl)-7-chloroquinolin-4-amine derivatives, synthesized by thermal and ultrasonic means, are endowed with anti-Zika virus activity.
Barbosa-Lima G, da Silveira Pinto LS, Kaiser CR, Wardell JL, De Freitas CS, Vieira YR, Marttorelli A, Cerbino Neto J, Bozza PT, Wardell SMSV, de Souza MVN, Souza TML. Barbosa-Lima G, et al. Among authors: kaiser cr. Eur J Med Chem. 2017 Feb 15;127:434-441. doi: 10.1016/j.ejmech.2017.01.007. Epub 2017 Jan 6. Eur J Med Chem. 2017. PMID: 28092859
Evaluation of 7-arylaminopyrazolo[1,5-a]pyrimidines as anti-Plasmodium falciparum, antimalarial, and Pf-dihydroorotate dehydrogenase inhibitors.
Azeredo LFSP, Coutinho JP, Jabor VAP, Feliciano PR, Nonato MC, Kaiser CR, Menezes CMS, Hammes ASO, Caffarena ER, Hoelz LVB, de Souza NB, Pereira GAN, Cerávolo IP, Krettli AU, Boechat N. Azeredo LFSP, et al. Among authors: kaiser cr. Eur J Med Chem. 2017 Jan 27;126:72-83. doi: 10.1016/j.ejmech.2016.09.073. Epub 2016 Sep 30. Eur J Med Chem. 2017. PMID: 27744189
Anti-Mycobacterial Evaluation of 7-Chloro-4-Aminoquinolines and Hologram Quantitative Structure-Activity Relationship (HQSAR) Modeling of Amino-Imino Tautomers.
Bispo MLF, Lima CHS, Cardoso LNF, Candéa ALP, Bezerra FAFM, Lourenço MCS, Henriques MGMO, Alencastro RB, Kaiser CR, Souza MVN, Albuquerque MG. Bispo MLF, et al. Among authors: kaiser cr. Pharmaceuticals (Basel). 2017 Jun 9;10(2):52. doi: 10.3390/ph10020052. Pharmaceuticals (Basel). 2017. PMID: 28598408 Free PMC article.
134 results