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Microglial inclusions and neurofilament light chain release follow neuronal α-synuclein lesions in long-term brain slice cultures.
Barth M, Bacioglu M, Schwarz N, Novotny R, Brandes J, Welzer M, Mazzitelli S, Häsler LM, Schweighauser M, Wuttke TV, Kronenberg-Versteeg D, Fog K, Ambjørn M, Alik A, Melki R, Kahle PJ, Shimshek DR, Koch H, Jucker M, Tanriöver G. Barth M, et al. Among authors: kahle pj. Mol Neurodegener. 2021 Aug 11;16(1):54. doi: 10.1186/s13024-021-00471-2. Mol Neurodegener. 2021. PMID: 34380535 Free PMC article.
Suppression of MAP kinases inhibits microglial activation and attenuates neuronal cell death induced by alpha-synuclein protofibrils.
Wilms H, Rosenstiel P, Romero-Ramos M, Arlt A, Schäfer H, Seegert D, Kahle PJ, Odoy S, Claasen JH, Holzknecht C, Brandenburg LO, Deuschl G, Schreiber S, Kirik D, Lucius R. Wilms H, et al. Among authors: kahle pj. Int J Immunopathol Pharmacol. 2009 Oct-Dec;22(4):897-909. doi: 10.1177/039463200902200405. Int J Immunopathol Pharmacol. 2009. PMID: 20074453 Free article.
Neuropathology in mice expressing mouse alpha-synuclein.
Rieker C, Dev KK, Lehnhoff K, Barbieri S, Ksiazek I, Kauffmann S, Danner S, Schell H, Boden C, Ruegg MA, Kahle PJ, van der Putten H, Shimshek DR. Rieker C, et al. Among authors: kahle pj. PLoS One. 2011;6(9):e24834. doi: 10.1371/journal.pone.0024834. Epub 2011 Sep 26. PLoS One. 2011. PMID: 21966373 Free PMC article.
Overexpression of the calpain-specific inhibitor calpastatin reduces human alpha-Synuclein processing, aggregation and synaptic impairment in [A30P]αSyn transgenic mice.
Diepenbroek M, Casadei N, Esmer H, Saido TC, Takano J, Kahle PJ, Nixon RA, Rao MV, Melki R, Pieri L, Helling S, Marcus K, Krueger R, Masliah E, Riess O, Nuber S. Diepenbroek M, et al. Among authors: kahle pj. Hum Mol Genet. 2014 Aug 1;23(15):3975-89. doi: 10.1093/hmg/ddu112. Epub 2014 Mar 11. Hum Mol Genet. 2014. PMID: 24619358 Free PMC article.
α-Synuclein oligomers pump it up!
Kahle PJ, Sugeno N, Skodras A. Kahle PJ, et al. EMBO J. 2015 Oct 1;34(19):2385-7. doi: 10.15252/embj.201592770. Epub 2015 Sep 15. EMBO J. 2015. PMID: 26373315 Free PMC article.
Neurofilament Light Chain in Blood and CSF as Marker of Disease Progression in Mouse Models and in Neurodegenerative Diseases.
Bacioglu M, Maia LF, Preische O, Schelle J, Apel A, Kaeser SA, Schweighauser M, Eninger T, Lambert M, Pilotto A, Shimshek DR, Neumann U, Kahle PJ, Staufenbiel M, Neumann M, Maetzler W, Kuhle J, Jucker M. Bacioglu M, et al. Among authors: kahle pj. Neuron. 2016 Jul 6;91(1):56-66. doi: 10.1016/j.neuron.2016.05.018. Epub 2016 Jun 9. Neuron. 2016. PMID: 27292537 Free article.
Neurofilament Light Chain in Blood and CSF as Marker of Disease Progression in Mouse Models and in Neurodegenerative Diseases.
Bacioglu M, Maia LF, Preische O, Schelle J, Apel A, Kaeser SA, Schweighauser M, Eninger T, Lambert M, Pilotto A, Shimshek DR, Neumann U, Kahle PJ, Staufenbiel M, Neumann M, Maetzler W, Kuhle J, Jucker M. Bacioglu M, et al. Among authors: kahle pj. Neuron. 2016 Jul 20;91(2):494-496. doi: 10.1016/j.neuron.2016.07.007. Epub 2016 Jul 20. Neuron. 2016. PMID: 27477021 Free article. No abstract available.
132 results