Kahle KT - Search Results

1

Exome sequencing implicates genetic disruption of prenatal neuro-gliogenesis in sporadic congenital hydrocephalus.

Jin SC, Dong W, Kundishora AJ, Panchagnula S, Moreno-De-Luca A, Furey CG, Allocco AA, Walker RL, Nelson-Williams C, Smith H, Dunbar A, Conine S, Lu Q, Zeng X, Sierant MC, Knight JR, Sullivan W, Duy PQ, DeSpenza T, Reeves BC, Karimy JK, Marlier A, Castaldi C, Tikhonova IR, Li B, Peña HP, Broach JR, Kabachelor EM, Ssenyonga P, Hehnly C, Ge L, Keren B, Timberlake AT, Goto J, Mangano FT, Johnston JM, Butler WE, Warf BC, Smith ER, Schiff SJ, Limbrick DD Jr, Heuer G, Jackson EM, Iskandar BJ, Mane S, Haider S, Guclu B, Bayri Y, Sahin Y, Duncan CC, Apuzzo MLJ, DiLuna ML, Hoffman EJ, Sestan N, Ment LR, Alper SL, Bilguvar K, Geschwind DH, Günel M, Lifton RP, Kahle KT. Jin SC, et al. Among authors: kahle kt. Nat Med. 2020 Nov;26(11):1754-1765. doi: 10.1038/s41591-020-1090-2. Epub 2020 Oct 19. Nat Med. 2020. PMID: 33077954 Free PMC article.

2

Molecular pathogenesis of inherited hypertension with hyperkalemia: the Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4.

Wilson FH, Kahle KT, Sabath E, Lalioti MD, Rapson AK, Hoover RS, Hebert SC, Gamba G, Lifton RP. Wilson FH, et al. Among authors: kahle kt. Proc Natl Acad Sci U S A. 2003 Jan 21;100(2):680-4. doi: 10.1073/pnas.242735399. Epub 2003 Jan 6. Proc Natl Acad Sci U S A. 2003. PMID: 12515852 Free PMC article.

3

WNK1, a kinase mutated in inherited hypertension with hyperkalemia, localizes to diverse Cl- -transporting epithelia.

Choate KA, Kahle KT, Wilson FH, Nelson-Williams C, Lifton RP. Choate KA, et al. Among authors: kahle kt. Proc Natl Acad Sci U S A. 2003 Jan 21;100(2):663-8. doi: 10.1073/pnas.242728499. Epub 2003 Jan 8. Proc Natl Acad Sci U S A. 2003. PMID: 12522152 Free PMC article.

4

WNK4 regulates the balance between renal NaCl reabsorption and K+ secretion.

Kahle KT, Wilson FH, Leng Q, Lalioti MD, O'Connell AD, Dong K, Rapson AK, MacGregor GG, Giebisch G, Hebert SC, Lifton RP. Kahle KT, et al. Nat Genet. 2003 Dec;35(4):372-6. doi: 10.1038/ng1271. Epub 2003 Nov 9. Nat Genet. 2003. PMID: 14608358

5

WNK4 regulates apical and basolateral Cl- flux in extrarenal epithelia.

Kahle KT, Gimenez I, Hassan H, Wilson FH, Wong RD, Forbush B, Aronson PS, Lifton RP. Kahle KT, et al. Proc Natl Acad Sci U S A. 2004 Feb 17;101(7):2064-9. doi: 10.1073/pnas.0308434100. Epub 2004 Feb 9. Proc Natl Acad Sci U S A. 2004. PMID: 14769928 Free PMC article.

6

WNK kinases: molecular regulators of integrated epithelial ion transport.

Kahle KT, Wilson FH, Lalioti M, Toka H, Qin H, Lifton RP. Kahle KT, et al. Curr Opin Nephrol Hypertens. 2004 Sep;13(5):557-62. doi: 10.1097/00041552-200409000-00012. Curr Opin Nephrol Hypertens. 2004. PMID: 15300163 Review.

7

Paracellular Cl- permeability is regulated by WNK4 kinase: insight into normal physiology and hypertension.

Kahle KT, Macgregor GG, Wilson FH, Van Hoek AN, Brown D, Ardito T, Kashgarian M, Giebisch G, Hebert SC, Boulpaep EL, Lifton RP. Kahle KT, et al. Proc Natl Acad Sci U S A. 2004 Oct 12;101(41):14877-82. doi: 10.1073/pnas.0406172101. Epub 2004 Oct 1. Proc Natl Acad Sci U S A. 2004. PMID: 15465913 Free PMC article.

8

Regulation of diverse ion transport pathways by WNK4 kinase: a novel molecular switch.

Kahle KT, Wilson FH, Lifton RP. Kahle KT, et al. Trends Endocrinol Metab. 2005 Apr;16(3):98-103. doi: 10.1016/j.tem.2005.02.012. Trends Endocrinol Metab. 2005. PMID: 15808806 Review.

9

Hypertension, age, and location predict rupture of small intracranial aneurysms.

Nahed BV, DiLuna ML, Morgan T, Ocal E, Hawkins AA, Ozduman K, Kahle KT, Chamberlain A, Amar AP, Gunel M. Nahed BV, et al. Among authors: kahle kt. Neurosurgery. 2005 Oct;57(4):676-83; discussion 676-83. Neurosurgery. 2005. PMID: 16239879

10

WNK3 modulates transport of Cl- in and out of cells: implications for control of cell volume and neuronal excitability.

Kahle KT, Rinehart J, de Los Heros P, Louvi A, Meade P, Vazquez N, Hebert SC, Gamba G, Gimenez I, Lifton RP. Kahle KT, et al. Proc Natl Acad Sci U S A. 2005 Nov 15;102(46):16783-8. doi: 10.1073/pnas.0508307102. Epub 2005 Nov 7. Proc Natl Acad Sci U S A. 2005. PMID: 16275911 Free PMC article.

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